Evidence map›Paper›PMID 40470282›Full record

ArticleFrontiers in veterinary science2025

In-field nucleic acid testing for porcine epidemic diarrhea virus with lateral flow immunoassay.

Wencong Chen, Jiahao Chen, Danni Ye, Xueyan Ai, Jiayi Luo, Chenxi Fang, Meihua Xiang, Maopeng Wang

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wencong ChenWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Jiahao ChenWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Danni YeWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Xueyan AiWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Jiayi LuoWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Chenxi FangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.
Meihua XiangResearch and Development Department, Hangzhou Goodhere Biotechnology Co., Ltd., Hangzhou, China.
Maopeng WangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Chashan University Town, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea is a significant disease that damages the global pig industry. The delay between infection and vaccination allows for a 30-70% mortality rate among piglets. Early virus detection is a more effective disease management strategy for pigs. Unfortunately, most methods rely heavily on skilled personnel and sophisticated equipment, which is not ideal in scenarios requiring cost reduction and efficiency. To address these challenges, our study based on one-step RT-PCR and lateral flow strips developed a reliable, field-deployable, and low-cost nucleic acid detection method for PEDV. The whole process takes about 45 min and the testing cost of each sample is low to $0.3. Moreover, this method is simple to operate, it is possible to complete the entire operation without training. Our clinical application demonstrates a robust diagnostic tool for detecting PEDV in field conditions, thereby providing more time for PEDV epidemic emergency response.

Indexed as

in-field detectionlateral flow immunoassayM genemicrofluidic chipPEDV

Identifiers

PMID40470282
PMCPMC12135921

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.