ArticleFrontiers in veterinary science2025
Retrospective evaluation of left ventricular eccentricity index in the assessment of precapillary pulmonary hypertension in dogs (2017-2021): 145 cases.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To determine interobserver variability of left ventricular eccentricity indices measurements in systole (EIs), diastole (EId) and at maximum flattening (EIm) by emergency and critical care residents on prerecorded cineloops in dogs with or without pulmonary hypertension. To assess whether these EI measurements allow to identify dogs with right heart changes compatible with moderate to severe pulmonary hypertension (PAH). Methods: Multicenter, retrospective, case-control study from 2017 to 2021. Medical records of dogs with stage B1 myxomatous mitral valve disease (MMVD) and dogs diagnosed with precapillary pulmonary hypertension (PCPH) via echocardiograms were reviewed. Dogs were categorized by a cardiologist into five groups (normal, B1 MMVD, mild, moderate, and severe PCPH) based on Doppler pulmonary pressure gradients and right heart morphology. Four blinded emergency and critical care residents measured EIs, EId and EIm. Results: One hundred and forty-five client-owned dogs were included. Interobserver agreement was strong, with an intraclass correlation coefficient (ICC) of 0.737 (95% CI: 0.621-0.852) across all eccentricity indices for the full study population and 0.768 (0.642-0.856) for the PAH group specifically. EIs, EId, and EIm were significantly higher in the PAH group compared to control and MMVD groups ( Conclusions: This study showed good inter-observer agreement of EIs, EIm, and EId measurement by ECC residents on prerecorded loops. EI allowed good identification of dogs with moderate to severe PAH by ECC residents.
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