Evidence map›Paper›PMID 40470223›Full record

ArticleResearch square2025

Din Oversees Mesenchymal Stem Cell Homeostasis in Mouse Incisors.

Xiaofang Wang, Changchun Dong, Bikash Lamichhane, Sanjaya Thapa, Yongxu Zhang, Shreyan Gupta, James J Cai

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaofang WangTexas A&M University College of Dentistry.ORCID 0000-0002-7370-7192
Changchun DongTexas A&M University College of Dentistry.
Bikash LamichhaneNational Institute of Dental & Craniofacial Research.
Sanjaya ThapaTexas A&M University College of Dentistry.
Yongxu ZhangTexas A&M University College of Dentistry.
Shreyan GuptaTexas A&M University.
James J CaiTexas A&M University.

Funding

A novel GTPase regulator governing the regenerative capacity of murine teethR01DE033676 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI XIAOFANG WANG · 2024 to 2026
$1.0M
NIDCR NIH HHS R01 DE033676
6 · The paper itself

Abstract

The murine incisor presents an excellent model for investigating stem cell homeostasis due to its regenerative capacity and continuous growth throughout the lifetime. Proper homeostasis of the dental epithelial stem cells (ESCs) and mesenchymal stem cells (MSCs) is pivotal for the continuous growth, tissue turnover and injury healing in murine incisors. By employing a newly developed knockout mouse model, we revealed that a predicted gene,

Identifiers

PMID40470223
PMCPMC12136219

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.