Evidence map›Paper›PMID 40470158›Full record

ArticleERJ open research2025

A composite score of polygraphic oximetry parameters predicts left ventricular hypertrophy in patients with obstructive sleep apnoea.

Matteo Landolfo, Federico Giulietti, Francesco Spannella, Silvia Sarnari, Chiara Di Pentima, Piero Giordano, Riccardo Sarzani

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matteo LandolfoDepartment of Clinical and Molecular Sciences, Centre of Obesity, "Politecnica delle Marche" University, Ancona, Italy.ORCID https://orcid.org/0000-0002-2087-2573
Federico GiuliettiInternal Medicine and Geriatrics, "Hypertension Excellence Centre" of the European Society of Hypertension, IRCCS INRCA, Ancona, Italy.
Francesco SpannellaDepartment of Clinical and Molecular Sciences, Centre of Obesity, "Politecnica delle Marche" University, Ancona, Italy.ORCID https://orcid.org/0000-0002-1846-7819
Silvia SarnariDepartment of Clinical and Molecular Sciences, Centre of Obesity, "Politecnica delle Marche" University, Ancona, Italy.
Chiara Di PentimaInternal Medicine and Geriatrics, "Hypertension Excellence Centre" of the European Society of Hypertension, IRCCS INRCA, Ancona, Italy.
Piero GiordanoInternal Medicine and Geriatrics, "Hypertension Excellence Centre" of the European Society of Hypertension, IRCCS INRCA, Ancona, Italy.
Riccardo SarzaniDepartment of Clinical and Molecular Sciences, Centre of Obesity, "Politecnica delle Marche" University, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obstructive sleep apnoea (OSA) is linked to cardiovascular disease (CVD). The obstructive apnoea-hypopnoea index (oAHI) used for diagnosing and grading OSA has limitations in predicting CVD. The present study assessed and compared the association between nocturnal hypoxaemia parameters and left ventricular hypertrophy (LVH). Methods: A cross-sectional study was conducted on 187 consecutive adult outpatients diagnosed with OSA after home cardiorespiratory polygraphy. Blood pressure control was tested with ambulatory blood pressure monitoring. A standard transthoracic cardiac ultrasound examination assessed LVH. Oximetry parameters were grouped into a single parameter (Oxy-score) using factor analysis (a higher Oxy-score indicating better nocturnal oxygenation), which was tested for association with LVH. Results: The mean age was 60±12 years, with 75% male sex and 94% overweight/obese. The prevalence of arterial hypertension and LVH was 92% and 75%, respectively. The prevalence of severe OSA was 44%, with a mean oAHI of 32±19. Patients with LVH had significantly higher oAHI (34±19 Conclusion: Nocturnal oximetry parameters, grouped into a single parameter as a proxy of the global hypoxic burden, proved to be a better and independent predictor of LVH than oAHI, supporting the pivotal relevance of oximetry parameters beyond oAHI in patients with OSA.

Identifiers

PMID40470158
PMCPMC12134923

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