Evidence map›Paper›PMID 40470147›Full record

ArticleERJ open research2025

Poor clinical outcomes in respiratory viral sepsis: a retrospective observational study.

Wenhao Cao, Jiuyang Xu, Zhengping Liu, Ziming Wang, Xueyang Zhang, Qingyuan Zhan, Bin Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenhao CaoNational Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Jiuyang XuNational Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-1906-5918
Zhengping LiuNational Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Ziming WangPeking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
Xueyang ZhangDepartment of Internal Medicine, Peking Union Medical College Hospital, Beijing, China.
Qingyuan ZhanNational Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-0021-0270
Bin CaoNational Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study attempts to explore the clinical differences of sepsis caused by respiratory viruses and bacteria, and to search for risk factors for mortality in viral sepsis. Methods: This single-centre, retrospective cohort study enrolled patients hospitalised at our medical intensive care unit (ICU) from October 2020 to January 2024 who were diagnosed with pneumonia and sepsis. The primary and secondary pathogens were identified with comprehensive aetiological tests. The baseline clinical information, biochemical tests, treatments and clinical outcomes were collected. Results: This study included 292 patients, comprising 191 with viral sepsis and 101 with bacterial sepsis. Compared with the bacterial sepsis group, patients with respiratory viral sepsis had lower oxygenation index levels upon ICU admission, higher proportions of acute respiratory distress syndrome (85% Conclusions: ICU patients with respiratory viral sepsis presented a higher incidence of unfavourable outcome, which may partially be attributed to secondary infections.

Identifiers

PMID40470147
PMCPMC12134930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.