Evidence map›Paper›PMID 40470111›Full record

ReviewInternational journal of nanomedicine2025

Targeted Nanoparticle-Based Therapies for Nasopharyngeal Carcinoma: Enhancing Radiosensitization, Photothermal Therapy, and Diagnostics.

Tianzhu Wang, Huanliang Wu, Liang Wang, Nana Lou, Lijuan Guo

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tianzhu WangThe Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People's Republic of China.
Huanliang WuThe Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People's Republic of China.
Liang WangThe Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People's Republic of China.
Nana LouThe Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People's Republic of China.
Lijuan GuoDepartment of Radiotherapy, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) remains a major clinical challenge due to its high resistance to conventional therapies such as chemotherapy and radiotherapy. Nanoparticle (NP)-based technologies have emerged as promising tools to enhance the efficacy of NPC treatment through mechanisms like radiosensitization and photothermal therapy. This review discusses the potential of NPs, particularly metal-based nanoparticles (gold and iron oxide), in improving the therapeutic outcomes of radiotherapy by overcoming tumor hypoxia and increasing radiation absorption. Additionally, we explore the application of NPs in photothermal therapy, wherein nanoparticles absorb light and generate localized heat to target tumor cells with precision. NPs are also playing an increasingly vital role in early diagnosis and real-time imaging, enabling more effective monitoring and personalized treatment. Despite the promising potential, challenges as nanoparticle biocompatibility, toxicity, and efficient targeting remain obstacles for clinical translation. In this review, we aim to provide a comprehensive summary of the current state of targeted nanoparticle-based interventions in NPC therapy and to outline the potential for these technologies to improve therapeutic outcomes.

Indexed as

NanoparticlesNasopharyngeal CarcinomaNasopharyngeal NeoplasmsPhotothermal TherapyRadiation-Sensitizing AgentsAnimalsGoldHumansMetal NanoparticlesGoldRadiation-Sensitizing Agentsnanomedicinenanoparticlenanotechnologynasopharyngeal carcinomatreatment

Identifiers

PMID40470111
PMCPMC12134383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.