ArticleFrontiers in medicine2025
Renal arteriolosclerosis impact on clinicopathological features and outcomes of idiopathic membranous nephropathy: a retrospective cohort analysis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Prognostic Stratification in Primary Glomerulonephritis: Integrating Histology, Biomarkers, and Risk Prediction Models.Life (Basel, Switzerland) · 2026Review
- Prognostic value of a composite histologic score in glomerular diseases: a 10-year single center cohort study.BMC nephrology · 2026Article
- Clinical effect of obinutuzumab in the treatment of idiopathic membranous nephropathy.American journal of translational research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To investigate the clinicopathological features and prognostic factors of idiopathic membranous nephropathy (IMN) patients with renal arteriolosclerosis, providing evidence for individualized clinical management. Methods: A retrospective analysis was conducted on 597 biopsy-confirmed IMN patients at Guangdong Provincial Hospital of Chinese Medicine from January 1, 2012, to December 31, 2022. Patients were stratified into two groups based on the presence of renal arteriolosclerosis. Clinical and pathological characteristics were compared between groups. Kaplan-Meier curves were used to assess cumulative renal remission rates, and Cox regression analysis was performed to identify risk factors for composite endpoint events in IMN patients with arteriolosclerosis. Results: In a cohort of 597 IMN patients (55.6% male), significant baseline differences were observed in Serum Sodium, triglycerides, membranous nephropathy (MN) stage, mesangial proliferation, interstitial fibrosis, and IgG deposition between the arteriolosclerosis and non-arteriolosclerosis groups ( Conclusion: Renal arteriolosclerosis portends poorer prognosis in IMN, with distinct clinicopathological features and accelerated renal function decline. Age, elevated creatinine, intense immune complex deposition, and advanced tubular-interstitial damage represent critical risk markers, highlighting the need for early vascular assessment and histology-guided risk stratification in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.