SynthesisFrontiers in medicine2025
Bibliometric analysis of research on intestinal flora and primary biliary cholangitis published between 2004 and 2024 using VOSviewer and CiteSpace visualization.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Osteoporosis in primary biliary cholangitis: from cholestasis to fracture prevention.Clinical and experimental hepatology · 2026Review
- Global Research Trends in Nutritional Management of Gastrointestinal Cancers: a 2004-2024 Bibliometric and knowledge-mapping Analysis.Journal of gastrointestinal cancer · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Increasing evidence suggests that the onset and progression of primary biliary cholangitis (PBC) are closely linked to changes in gut microbiota, including bacterial translocation, molecular mimicry, and immune regulation. This study aimed to conduct a bibliometric analysis of the frontiers and hotspots of research on the relationship between gut microbiota and PBC between 2004 and 2024. Methods: A bibliometric study was conducted by searching the Web of Science database for articles on intestinal flora and PBC published between 2004 and 2024. Excel, VOSviewer, and CiteSpace were used for econometric analysis and visualization of the identified articles. Results: Between 2004 and 2024, 167 articles focusing on intestinal flora and PBC were published. The number of publications in this field maintained an upward trend over the years, with China and the United States contributing the highest number of articles. The United States had the highest total number of citations, and the institution with the most publications in the United States was the University of California Davis, with the team led by Professor Gershwin contributing the greatest number of articles. Conclusion: There is a correlation between gut microbiota and PBC, and the role of gut microbiota in the pathogenesis and treatment of PBC will continue to be a future research direction. Targets such as bile acids and farnesoid X receptors are also current research hotspots.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.