ArticleInternational journal of women's health2025
Vitamin D, Homocysteine, and Thyroid Dysfunction as Risk Factors for Missed Abortion: A Retrospective Risk Factor Analysis.
Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Analysis of metabolites in serum and villous tissue of missed abortion patients based on targeted metabolomics.Frontiers in endocrinology · 2026Article
- Analysis of Risk Factors and Prediction Model of Chromosomal Abnormalities in Embryos from Patients with Missed Miscarriage.International journal of women's health · 2025Article
- Effects of oral and transdermal estrogen on postoperative endometrial recovery after missed abortion: a retrospective longitudinal cohort study.Frontiers in medicine · 2025Article
- Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.Women's health (London, England)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to identify potential associations between missed abortion (MA) and risk factors, including low levels of vitamin D, high homocysteine, and abnormal thyroid function, among women undergoing early pregnancy assessments, thereby bridging the clinical knowledge gap regarding modifiable risk factors for MA. Methods: This retrospective study analyzed serum levels of vitamin D, (25-(OH)-D3), homocysteine (Hcy), and thyroid hormones (thyroid-stimulating hormone [TSH], thyroid peroxidase antibodies [TPOAb]) in 158 women who experienced missed abortion compared to 237 women with normal early pregnancy outcomes. Results: MA patients had significantly lower vitamin D levels (P = 0.04), higher Hcy (P < 0.05), and evidence of abnormal thyroid function, including TSH levels ≥ 4 mIU/L (P = 0.01) and positive TPOAb (P = 0.02). Low vitamin D was significantly associated with an increased risk of MA (odds ratio = 1.8; P = 0.03). Conclusion: These findings suggest that low vitamin D levels may be a potential risk factor for MA, highlighting the importance of monitoring and supplementation in early pregnancy to reduce the risk of missed abortion. As this study is retrospective, it cannot establish causality between the identified factors and MA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.