ArticleJournal of asthma and allergy2025
Bibliometric Analysis on the Central Regulation of Airway Allergic Hyperreactivity Diseases Based on Bibliometric Analysis: From Lung-Brain Axis to Nasal-Brain Axis.
Article in Journal of asthma and allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- From Bibliometrics to Preliminary Clinical Evidence: TRP Channel-Mediated Neuroimmune Crosstalk in Temperature-Sensitive Airway Hyperresponsiveness.Journal of inflammation research · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aimed to systematically analyze the neuro-regulation mechanisms of airway hyperreactivity disease using bibliometrics, focusing on the research status and progress of two key regulatory networks: the "lung-brain axis" and the "nasal-brain axis", to further characterize the "nasal-brain axis". Methods: A bibliometric analysis of 626 articles published between 1991 and 2024 was conducted to assess the growing interest in the impact of neuro-immune mechanisms and psychological stress on airway diseases, including asthma and allergic rhinitis (AR). Results: The study findings revealed that interactions between neuro-immune signaling pathways and the central nervous system are crucial for understanding airway hyperreactivity, with the United States leading research contributions. Key themes identified in this study include allergic asthma, neuroinflammation, and the lung-brain axis, revealing bidirectional communication pathways between peripheral and central immune responses. Conclusion: Based on studies of asthma and the lung-brain axis, we anticipate that AR and the nasal-brain axis likely involve similar neuro-immune mechanisms and peripheral-central response circuits. The nasal-brain axis theory was further supported by its integration with the unified airway hypothesis, solidifying its role as a crucial regulatory mechanism in airway inflammation research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.