Evidence map›Paper›PMID 40469820›Full record

ArticleInternational journal of clinical pediatric dentistry2025

Comparison of Success of Glass Ionomer Cements with Calcium Hydroxide and Tricalcium Silicate Cements in Indirect Pulp Treatments of Molars in Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Shreyas Neelkanthan, Ashwin M Jawdekar, Laresh N Mistry

Abstract read
In one paragraph

Article in International journal of clinical pediatric dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effect of Titanium Dioxide (TiOMaterials (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shreyas NeelkanthanDepartment of Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0009-0008-4057-3045
Ashwin M JawdekarDepartment of Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0002-9948-9007
Laresh N MistryDepartment of Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0002-9770-3532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Biological materials such as glass ionomer cement (GIC), calcium hydroxide cement (Ca(OH)₂) and tricalcium silicate cement (TCS) have been effective in the indirect pulp treatment (IPT) of advanced carious lesions in molars. GIC has been in use for a long time as a biomimetic material with the added advantage of fluoride release for the treatment of the same. Objectives: Our study compared the success of GIC vs Ca(OH)₂ and TCS in IPT of molars in primary and permanent teeth in 4-18-year-old children. Search: Two researchers, SN and AMJ, independently searched the literature using appropriate keyword combinations, and conflicts were resolved by a third author, LNM. The search was conducted using PubMed and extended to other search engines. Selection criteria: Randomized controlled trials (RCTs) (both split-mouth and parallel-arm), reported in or with full translations available in English, and a follow-up period of at least 6 months were included. Children aged 4-18 years with carious molars (primary and permanent) who had received IPTs with GIC and other cements were included. Data collection and analysis: A data extraction sheet was prepared to include all details. The risk of bias (RoB) was assessed using the Cochrane RoB 2 tool. Publication bias was assessed using funnel plot analysis. Meta-analysis were conducted using forest plots. The certainty of evidence was reported using the GRADE method. RevMan 5.4 software was used. Results: The success of GIC was compared with Ca(OH)₂ and TCS in IPT. Three studies were included in the meta-analysis; the pooled success of GIC vs Ca(OH)₂ [OR (95% CI)] 1.02 (0.29, 3.61) ( Conclusion: The overall success of GIC IPT was 96%. GIC was comparable to Ca(OH)₂ and TCS. The RoB was moderate, and publication bias was unascertained. How to cite this article: Neelkanthan S, Jawdekar AM, Mistry LN. Comparison of Success of Glass Ionomer Cements with Calcium Hydroxide and Tricalcium Silicate Cements in Indirect Pulp Treatments of Molars in Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Int J Clin Pediatr Dent 2025;18(4):473-478.

Indexed as

Calcium hydroxide cementsGlass ionomer cementsIndirect pulp treatmentsPartial caries excavationPulp protectionSelective caries removalTricalcium silicate cements

Identifiers

PMID40469820
PMCPMC12131065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.