Evidence map›Paper›PMID 40469719›Full record

ArticleFrontiers in microbiology2025

Evaluation of kefir consumption on gut microbial diversity in a healthy young population using full-length 16S rRNA sequencing.

Yejin Choi, Gi Beom Keum, Juyoun Kang, Hyunok Doo, Jinok Kwak, Haram Kim, Yeongjae Chae, Suyoung Lee, Hyunjin Yang, Sheena Kim and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07682077 (Effects of a Kefir Intervention in Pregnancy on Glucose, Insulin, Gestational Diabetes Mellitus, and the Gut Microbiome and Metabolites), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07682077 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of a Kefir Intervention in Pregnancy on Glucose, Insulin, Gestational Diabetes Mellitus, and the Gut Microbiome and Metabolites: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of New BrunswickRan2026 to 2029Enrolled60ConditionsGestational Diabetes Mellitus (GDM), Blood Glucose, Insulin Resistance, Diabetes, Gut MicrobiomeArmsKefir
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yejin Choi *Departement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Gi Beom Keum *Departement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Juyoun Kang *Departement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Hyunok DooDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Jinok KwakDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Haram KimDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Yeongjae ChaeDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Suyoung LeeDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Hyunjin YangDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Sheena KimDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Xingmin SunDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Hyeun Bum KimDepartement of Animal Biotechnology, Dankook University, Chenonan-si, Republic of Korea.
Soo Jin YooDepartment of Laboratory Medicine, Sanggye Paik Hospital, Inje University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A balanced gut microbiota is essential for maintaining digestive, immune, and metabolic health. Kefir, a fermented milk beverage, influences gut microbiota through its probiotic composition and bioactive compounds, exhibiting various health-promoting effects. However, evidence on the effects of kefir on gut microbiota, particularly in healthy populations, is still limited. This study aimed to elucidate the effects of kefir on gut microbiota composition in healthy young adults under a controlled dietary environment. Methods: In this randomized, controlled, parallel-group trial, 28 healthy participants aged 18-30 years were assigned to one of three groups: kefir ( Results: Kefir consumption increased the relative abundance of lactate-producing bacteria, including Discussion: In summary, this study highlights kefir's potential to modulate gut microbiota composition in healthy individuals, emphasizing its role in supporting gut health.

Indexed as

16S rRNA sequencinggut healthgut microbiotahealthy young adultkefirprobioticsshort-chain fatty acids (SCFAs)

Identifiers

PMID40469719
PMCPMC12134070

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.