Evidence map›Paper›PMID 40469676›Full record

ArticleFrontiers in nutrition2025

Non-linear association between serum vitamin D and bacterial vaginosis in U.S. women: analysis from NHANES 2001-2004.

Ming Liu, Jingyu Xiang, Miao Zhang, Yifang Zhang, Jian Liu

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ming LiuDepartment of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Jingyu XiangDepartment of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Miao ZhangDepartment of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Yifang ZhangDepartment of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Jian LiuDepartment of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have reported inconsistent associations between serum vitamin D levels and bacterial vaginosis (BV). Therefore, this study aimed to comprehensively investigate the relationship between serum vitamin D concentrations and BV risk among adult women in the United States. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) 2001-2004 were analyzed. Multivariate logistic regression was used to assess the association between serum vitamin D levels and BV. Additionally, smoothing curve fitting and subgroup analyses were performed to explore potential non-linear relationships and effect modifications. Results: A total of 1,397 adult women were included. After adjusting for multiple covariates, serum vitamin D levels showed a significant non-linear negative association with BV risk. Subgroup analyses revealed that this association was not statistically significant among certain ethnic groups and women with lower body mass index (BMI). Conclusion: Serum vitamin D levels were non-linearly and negatively associated with the risk of bacterial vaginosis in adult women in the United States. Notably, the association was no longer present at serum vitamin D concentrations ≥63.1 nmol/L, which may inform future research.

Indexed as

bacterial vaginosiscross-sectional studyNHANESnutrientsserum vitamin D

Identifiers

PMID40469676
PMCPMC12133536

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