ArticleFrontiers in nutrition2025
Sex differences in the impact of controlling nutritional status score on diabetic retinopathy: findings of 2003-2018 National Health and Nutrition Examination Survey.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Residual cholesterol correlates with mild cognitive impairment, particularly for executive dysfunction among male individuals with type 2 diabetes mellitus.Frontiers in endocrinology · 2026Article
- Sex differences in the association between the uric acid to high density lipoprotein cholesterol ratio and mild cognitive impairment in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2025Article
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5 authors.
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Abstract
Background: Nutritional status plays a crucial role in the progression of diabetes complications. This study assessed sex differences in Controlled Nutritional Status (CONUT) score and diabetic retinopathy (DR). Methods: Clinical data between 2003 and 2018 were retrieved from the National Health Nutritional Examination Survey (NHANES) database. The association of CONUT score with DR was analyzed by multivariate weighted logistic regression with restricted cubic splines (RCS). The impact of CONUT scores on DR outcomes in male and female patients was evaluated by subgroup analyses and interaction tests. Results: A total of 3,762 participants were included in this study. After adjusting for all covariates, a higher CONUT score was positively associated with DR risk in women (OR = 1.88, 95% CI: 1.13-3.15), while no significant association between CONUT score and DR was observed in male participants and the overall participant population. In addition, RCS regression showed a linear positive correlation between CONUT score and DR risk in women ( Conclusion: There is a sex difference in the link between higher CONUT scores and the prevalence of DR. Specifically, these findings highlight the importance of personalized nutritional intervention in women at high risk for DR.
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