Analogue information processing in NF-κB gene regulatory system.

Pankaj Gautam, Dinesh Kashyap, Debabrata Biswas, Sudipta Kumar Sinha

Abstract read

In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Analogue information processing in NF-κB gene regulatory system.Royal Society open science · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pankaj GautamDepartment of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab, India.

Dinesh KashyapDepartment of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab, India.

Debabrata BiswasDepartment of Physics, Bankura University, Bankura, West Bengal, India.

Sudipta Kumar SinhaDepartment of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab, India.ORCID https://orcid.org/0000-0002-9568-5676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear factor-κB (NF-κB) participates in various cellular processes to encompass cell fate through differential gene expression, but the underlying molecular mechanism behind this phenomenon is still elusive. Two factors in this process can control the gene expression for determining the cell's fate: (i) synthesized proteins may have a considerable lifetime and (ii) gene activation may be slow or delayed. To address the first factor, we argue that the NF-

Indexed as

bifurcation theorybiochemical networkscoloured noiseFokker–Planck equationstochastic gene expressiontime delay

Identifiers

PMID40469662

DOI10.1098/rsos.241487

PMCPMC12133345

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.