Evidence map›Paper›PMID 40469616›Full record

ArticleFrontiers in public health2025

Prevalence and risk factors of mild cognitive impairment and dementia in northern Peru.

Jonathan Zegarra-Valdivia, Leandro Pérez-Fernández, Milagros Casimiro-Arana, Harold Arana-Nombera, Viviana Nayelli Gallegos-Manayay, María Del Rosario Oliva-Piscoya, Reyna Alamo-Medina, Eduardo Abanto-Saldaña, Nobuko Vásquez-Zuñe, Lisseth Detquizan Pérez and 10 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jonathan Zegarra-ValdiviaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Leandro Pérez-FernándezFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Milagros Casimiro-AranaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Harold Arana-NomberaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Viviana Nayelli Gallegos-ManayayFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
María Del Rosario Oliva-PiscoyaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Reyna Alamo-MedinaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Eduardo Abanto-SaldañaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Nobuko Vásquez-ZuñeFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Lisseth Detquizan PérezFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Diana Gutierrez-FloresFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Leslie Lozada TantaricoFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Naydelin HernándezFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
María Celinda Cruz-OrdinolaFacultad de ciencias de la salud, Universidad Señor de Sipán, Chiclayo, Peru.
Carmen Paredes-ManriqueFacultad de psicología, Universidad Tecnológica del Perú, Lima, Peru.
Brenda Chino-VilcaCenter of Cognitive and Computational Neuroscience-UCM, Pozuelo de Alarcón, Madrid, Spain.
Gabriel EspinozaMinisterio De Salud MINSA, Lima, Peru.
José CabrejoHospital Nacional Almanzor Aguinaga Asenjo ES SALUD Chiclayo, Chiclayo, Peru.
Sheila Castro-SuarezCBI en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Nilton CustodioInstituto Peruano de Neurociencias, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Global dementia prevalence estimates indicate a growing burden, particularly in Low- and Middle-Income Countries (LMICs). Factors such as education, socioeconomic status, and limited public health interventions contribute to the development of Alzheimer's disease and other dementias. This study aimed to determine the prevalence of Mild Cognitive Impairment (MCI) and dementia in middle-aged and older adults from northern Peru, as well as identify possible associated risk factors. Methods: A cross-sectional study was conducted with 385 participants aged 40 to 85 years from Chiclayo, Peru. Cognitive impairment was assessed using the Rowland Universal Dementia Assessment Scale (RUDAS) and INECO Frontal Screening (IFS). Functional activity and depression were evaluated with the Pfeffer Functional Activities Questionnaire (PFAQ) and Patient Health Questionnaire-9 (PHQ-9). Participants were classified as controls, MCI, or dementia based on education-adjusted cutoff scores of those scales through cognitive system classification tools. Results: According to the results, 31.4% of the sample consisted of subjects without cognitive impairment, 40.5% were identified as possible cases of MCI, and 24.9% as possible cases of dementia. However, the percentages by age group are high. A lower educational level is associated with older age and correlates with lower cognitive scores and functional impairment. Age, hypertension, and hearing loss were significant risk factors for MCI and dementia. Conclusion: The prevalence of possible MCI and dementia in a city in north Peru is high, with a predominance of MCI and dementia in older adults. Age, low education, hypertension, and hearing loss are potential risk factors for cognitive impairment.

Indexed as

Cognitive DysfunctionDementiaAdultAgedAged, 80 and overCross-Sectional StudiesEducational StatusFemaleHumansMaleMiddle AgedPeruPrevalenceRisk FactorsSurveys and Questionnairescognitive declinedementiamild cognitive impairmentnorthern Peruprevalencerisk factors

Identifiers

PMID40469616
PMCPMC12133550

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.