Evidence map›Paper›PMID 40469518›Full record

ArticleiMeta2025

Age-specific reference intervals for plasma amino acids and their associations with nutrient intake in the Chinese pediatric population.

Yang Wen, Qing Liu, Hongbo Zeng, Lina Lyu, Xuezhen He, Xin Zhang, Wentao Lyu, Weijun Chen, Yingping Xiao

Abstract read
In one paragraph

Article in iMeta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang WenState Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition Zhejiang Academy of Agricultural Sciences Hangzhou China.
Qing LiuCollege of Biotechnology and Bioengineering Zhejiang University of Technology Hangzhou China.
Hongbo ZengState Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition Zhejiang Academy of Agricultural Sciences Hangzhou China.
Lina LyuDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou China.
Xuezhen HeChildren's Health Center, Beiyuan Community Service Center Yiwu China.
Xin ZhangDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou China.
Wentao LyuState Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition Zhejiang Academy of Agricultural Sciences Hangzhou China.
Weijun ChenDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou China.
Yingping XiaoState Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition Zhejiang Academy of Agricultural Sciences Hangzhou China.ORCID https://orcid.org/0000-0002-7949-1126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 2901 healthy Chinese children aged 0-12 years were enrolled in the reference group; 102 confirmed Phenylketonuria cases were included as validation individuals. Establishing the age-specific reference intervals of 42 plasma amino acids in Chinese pediatric populations. Profiling dynamic interactions between multiple nutrient intake and amino acid change patterns.

Identifiers

PMID40469518
PMCPMC12130562

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.