Evidence map›Paper›PMID 40469506›Full record

ArticleiMeta2025

A multi-centered prospective birth cohort study in Western China.

Xiangyu Li, Ying Wu, Bin Yi, Mengjie Chen, Gang Zhang, Xiaoshan Shao, Xiulian Jiang, Yuxia Cui, Li Chen, Xiaojing Dong and 25 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in iMeta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Xiangyu LiDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Ying WuChengdu Women's and Children's Central Hospital, School of Medicine University of Electronic Science and Technology of China Chengdu China.
Bin YiGansu Provincial Maternity and Child-Care Hospital (Gansu Provincial Central Hospital), Gansu Provincial Pediatric Clinical Research Center Lanzhou China.
Mengjie ChenThe Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Gang ZhangDepartment of Obstetrics Sichuan Provincial Women's and Children's Hospital, The Affiliated Women's and Children's Hospital of Chengdu Medical College Chengdu China.
Xiaoshan ShaoDepartment of Renal Rheumatology and Immunology Guiyang Maternal and Child Health Care Hospital Guiyang China.
Xiulian JiangQinghai Provincial Women and Children's Hospital Xining China.
Yuxia CuiShanghai Children's Medical Center Guizhou Hospital Shanghai Jiao Tong University School of Medicine Guiyang China.
Li ChenGrowth, Development and Mental Health Center of Children and Adolescents, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders Children's Hospital of Chongqing Medical University Chongqing China.
Xiaojing DongThe Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Shu ZhangDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Yao ZhaoDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Yuebi DengDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Xueqi LiGuangzhou National Laboratory Guangzhou China.
Yang WangDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Lei WuDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Yu FuDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Dan RanDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.
Chen PengGuangzhou National Laboratory Guangzhou China.
Xiao YangChengdu Women's and Children's Central Hospital, School of Medicine University of Electronic Science and Technology of China Chengdu China.
Lan ZhangChengdu Women's and Children's Central Hospital, School of Medicine University of Electronic Science and Technology of China Chengdu China.
Yanxia WangGansu Provincial Maternity and Child-Care Hospital (Gansu Provincial Central Hospital), Gansu Provincial Pediatric Clinical Research Center Lanzhou China.
Yi ZhuThe Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Dina SunThe Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Yuchen RanDepartment of Child Healthcare Sichuan Provincial Women's and Children's Hospital, The Affiliated Women's and Children's Hospital of Chengdu Medical College Chengdu China.
Dan ZhengDepartment of Maternity Health Guiyang Maternal and Child Health Care Hospital Guiyang China.
Xuan YinDepartment of Maternity Health Guiyang Maternal and Child Health Care Hospital Guiyang China.
Yufen ChenQinghai Provincial Women and Children's Hospital Xining China.
Yu LongShanghai Children's Medical Center Guizhou Hospital Shanghai Jiao Tong University School of Medicine Guiyang China.
Wenjing WangShanghai Children's Medical Center Guizhou Hospital Shanghai Jiao Tong University School of Medicine Guiyang China.
Xiaodong ZhaoDepartment of Rheumatism and Immunology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity Chongqing China.
Enmei LiuDepartment of Respiratory Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity Chongqing China.
Tao XuGuangzhou National Laboratory Guangzhou China.
Qiu LiDepartment of Nephrology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases Chongqing China.
Wen ZhongDepartment of Early Life Development and Cohort Research Laboratory Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases Chongqing China.ORCID https://orcid.org/0000-0002-7422-6104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Western China Birth Cohort (WCBC) is a large-scale, multi-centered, prospective birth cohort study designed to address critical gaps in maternal and child health research in Western China, a region with diverse altitudes, ethnic groups, and unique environmental exposures. WCBC had enrolled 15,093 pregnant women across eight clinical centers in five provinces (Qinghai, Gansu, Guizhou, Chongqing, and Sichuan), spanning from the high-altitude Qinghai-Tibet Plateau to lowland regions. WCBC has collected over 220,000 medical records, 80,000 questionnaires, and 12 different types of biological samples, including peripheral blood, cord blood, dried blood spots, placenta, umbilical cord, decidua, saliva, feces, throat and nasal swabs, vaginal swabs, and breast milk. By integrating advanced multi-omics measurement, including genomics, proteomics, exosome profiling, metabolomics, spatial transcriptomics, single-cell RNA sequencing, culturome, metagenomics, and virosome analysis, WCBC provides a valuable platform to explore gene-environment interplay, early-life determinants of health, and long-term disease risks in diverse populations in Western China.

Identifiers

PMID40469506
PMCPMC12130564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.