Evidence map›Paper›PMID 40469505›Full record

ArticleiMeta2025

Spaceflight redefines ageing-associated microbiota.

Yuan Sun, Sai Liu, Long Chen, Zheng Zhou, Mengyu Ma, Jinran Li, Yi Lu, Yiting Shi, Tingting Yao, Ruizhi Feng and 7 more

Abstract readLetter
In one paragraph

Article in iMeta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuan SunState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Sai LiuState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Long ChenState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Zheng ZhouDepartment of Computer Science RWTH Aachen University Aachen Germany.
Mengyu MaState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Jinran LiState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Yi LuState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Yiting ShiState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Tingting YaoState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Ruizhi FengState Key Laboratory of Reproduction Medicine and Offspring Health Nanjing Medical University Nanjing China.
Qiulun LuState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Fatimah QassadiSchool of Pharmacy The University of Nottingham Nottingham UK.
Philip M WilliamsSchool of Pharmacy The University of Nottingham Nottingham UK.
Tanya M MonaghanNIHR Nottingham Biomedical Research Centre University of Nottingham Nottingham UK.
Guangji WangState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Zheying ZhuSchool of Pharmacy The University of Nottingham Nottingham UK.
Xinuo LiState Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.ORCID 0009-0009-3455-1955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spaceflight reshapes microbiota and immune function, mitigating some ageing effects while accelerating immune aging, revealing crucial insights for astronaut health and longevity in space missions.

Identifiers

PMID40469505
PMCPMC12130553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.