Evidence map›Paper›PMID 40469488›Full record

ArticleEplasty2025

Rare Case of Pediatric Lower Limb Verrucous Venous Malformation: Treatment Approach and Considerations.

Annie Chen-Carrington, Adam Goodreau, Brian J Strife, Laurie Shinn, Jennifer Rhodes

Abstract readCase Reports
In one paragraph

Article in Eplasty, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annie Chen-CarringtonVirginia Commonwealth University School of Medicine, Richmond, Virginia.
Adam GoodreauVirginia Commonwealth University School of Medicine, Richmond, Virginia.
Brian J StrifeVirginia Commonwealth University School of Medicine, Richmond, Virginia.
Laurie ShinnCommonwealth Dermatology, Richmond, Virginia.
Jennifer RhodesVirginia Commonwealth University School of Medicine, Richmond, Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Verrucous venous malformation (VVM) is a rare, congenital, low-flow vascular anomaly composed of capillaries and veins in the dermis and subcutaneous tissues. Diagnosis is difficult because knowledge of cases is rare and typically identified with sonographic imaging and elevated GLUT-1. Treatment is mired by high rates of recurrence and residual pain, with further enlargement upon resection or injury. Current management strategies include a combination of laser therapy, surgery, cryotherapy, and topical steroids, each with varying rates of success. Methods: The authors examine a case of confirmed VVM, which was initially treated with a candela pulsed dye laser and propranolol to no avail. A combination of surgical approaches were chosen. Conclusions: We now look to topical sirolimus 1% as an adjunct for this patient with residual lesions. Questions remain as to the effectiveness, optimal dose, and duration of topical sirolimus and whether this combination of surgical and topical intervention will be effective in the treatment for VVM.

Indexed as

Plastic SurgerySirolimus Sy stemic MAP3 Kinase InhibitorsVerrucous HemangiomaVerrucous Venous Malformation

Identifiers

PMID40469488
PMCPMC12132595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.