Evidence map›Paper›PMID 40469481›Full record

ReviewEnvironmental science and ecotechnology2025

Global antibiotic hotspots and risks: A One Health assessment.

Bingshuang Yan, Fuyang Huang, Jiaolong Ying, Dafang Zhou, Samira Norouzi, Xianming Zhang, Bin Wang, Fei Liu

Abstract readReview
In one paragraph

Review in Environmental science and ecotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bingshuang YanSchool of Environment and Resource, Southwest University of Science and Technology, Mianyang, 621000, China.
Fuyang HuangSchool of Environment and Resource, Southwest University of Science and Technology, Mianyang, 621000, China.
Jiaolong YingHebei Center for Ecological and Environmental Geology Research, Hebei GEO University, Shijiazhuang, 050031, China.
Dafang ZhouSchool of Environment and Resource, Southwest University of Science and Technology, Mianyang, 621000, China.
Samira NorouziDepartment of Chemistry and Biochemistry, Concordia University, Montreal, H3G 1M8, Canada.
Xianming ZhangDepartment of Chemistry and Biochemistry, Concordia University, Montreal, H3G 1M8, Canada.
Bin WangSchool of Environment and Resource, Southwest University of Science and Technology, Mianyang, 621000, China.
Fei LiuKey Laboratory of Groundwater Conservation of MWR, China University of Geosciences (Beijing), Beijing, 100083, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are increasingly prevalent in global environments, driving antimicrobial resistance and disrupting microbial cycling. These impacts pose threats to human, animal, and environmental health. Therefore, addressing this emergent issue necessitates a One Health framework that integrates these interconnected dimensions. Here we systematically review 137 antibiotics across diverse global environmental compartments. We find that sulfonamides, macrolides, quinolones, and tetracyclines are globally ubiquitous, particularly prevalent in Asia and Africa, whereas β-lactams dominates in Europe. Hierarchical clustering revealed ten priority antibiotics in liquid phases and eight in solid phases requiring urgent attention. Regional analysis indicated the highest antibiotic concentrations within wastewater treatment plant liquids in the Americas and surface waters in Africa, with generally lower levels detected in Asia and Europe. Utilizing a One Health assessment framework, we integrated Predicted No-Effect Concentrations for antibiotic resistance selection (PNEC

Indexed as

Antibiotic resistance genesAntibioticsNitrogen cycleOne healthRisk assessment

Identifiers

PMID40469481
PMCPMC12136843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.