ArticleAcute medicine & surgery
Effect of closed negative pressure wound therapy after laparotomy for gastrointestinal perforation: A single-center observational study.
Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Prophylactic Incisional Negative Pressure Wound Therapy on Surgical Site Infection After Emergency Laparotomy: An Updated Meta-Analysis With Trial Sequential Analysis.World journal of surgery · 2026Pooled it
- Risk stratification of surgical site infection in high-risk spine surgery under prophylactic ciNPWT.BMC musculoskeletal disorders · 2026Observational
- Delayed primary closure versus subcutaneous suction drain with primary closure following contaminated laparotomy wound.Bioinformation · 2026Article
- A Systematic Review of Closed-Incision Negative-Pressure Wound Therapy for Hepato-Pancreato-Biliary Surgery: Updated Evidence, Context, and Clinical Implications.Journal of clinical medicine · 2025Review
- Effect of closed negative pressure wound therapy after laparotomy for gastrointestinal perforation: A single-center observational study.Acute medicine & surgeryArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: Laparotomy for gastrointestinal perforation is associated with a high risk of surgical site infection (SSI). The present study aimed to evaluate the effect of closed negative pressure wound therapy (NPWT) against SSI in patients undergoing laparotomy for gastrointestinal perforation. Methods: This single-center, retrospective, observational study was carried out in a tertiary emergency medical center. We performed closed NPWT following emergency laparotomy for gastrointestinal perforation between May 2019 and May 2024, and compared it to standard dressings used between January 2016 and April 2019. Cases of open abdominal management were excluded. The primary outcome was the incidence of superficial and deep SSI between the two groups. Results: The closed NPWT group comprised 65 patients, and the standard dressing group comprised 62 patients. There were no significant differences in patient characteristics, comorbidities, operative indications, and wound classification between the two groups. The rate of superficial and deep SSI was significantly lower with closed NPWT (26.2% with closed NPWT vs. 45.2% with standard dressing, Conclusion: The application of closed NPWT in patients undergoing laparotomy for gastrointestinal perforation was associated with a lower incidence of SSI compared with that of a standard surgical dressing.
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