Evidence map›Paper›PMID 40469347›Full record

ArticleSurgical neurology international2025

Diffuse bone-marrow metastasis of grade 4 isocitrate dehydrogenase-mutant astrocytoma associated with hematological abnormalities: Gliomatosis of the bone marrow.

Futa Ninomiya, Naoki Nitta, Mai Noujima, Suzuko Moritani, Tadateru Fukami, Kazushi Higuchi, Kazumichi Yoshida

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Futa NinomiyaDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Japan.
Naoki NittaDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Japan.
Mai NoujimaDepartment of Diagnostic Pathology, Shiga University of Medical Science, Otsu, Japan.
Suzuko MoritaniDepartment of Diagnostic Pathology, Shiga University of Medical Science, Otsu, Japan.
Tadateru FukamiDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Japan.
Kazushi HiguchiDepartment of Neurosurgery, Nagahama Red Cross Hospital, Nagahama, Japan.
Kazumichi YoshidaDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diffuse bone-marrow metastasis of high-grade glioma associated with hematological abnormalities is extremely rare. Case Description: A 32-year-old man was referred and admitted to our hospital for treatment of three remote recurrent brain lesions. He had been treated at the referring hospital for a primary brain tumor in the right frontal lobe. One of the recurrent lesions was resected and diagnosed as a grade 4 isocitrate dehydrogenase ( Conclusion: We present a rare case of diffuse bone-marrow metastasis of grade 4

Indexed as

Gliomatosis of the bone marrowHigh-grade gliomaLactate dehydrogenasePancytopeniaVertebral metastasis

Identifiers

PMID40469347
PMCPMC12134873

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.