ArticleSurgical neurology international2025
Adult-onset giant mediastinal neuroblastoma.
Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Neuroblastoma is a neurogenic tumor typically diagnosed in children <5 years of age. It arises from immature neural crest cells of the medulla of the adrenal gland or, less commonly, along the paravertebral sympathetic chain. We hereby report a patient with adult-onset giant mediastinal neuroblastoma. Case Description: A 34-year-old female presented with mid-thoracic back pain radiating to the ribs for 1 month. The neurological examination showed decreased sensation at the left T6-T12 dermatomes. Radiological imaging revealed a giant left mediastinal paravertebral soft-tissue lesion. The patient underwent a posterolateral thoracotomy and resection of the lesion. The histopathological sections were compatible with mediastinal neuroblastoma (Differentiating subtype). Conclusion: Adult-onset neuroblastoma has been rarely reported in the literature. The present article discusses the clinicoradiological features of an adult patient with giant mediastinal neuroblastoma.
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