Evidence map›Paper›PMID 40469318›Full record

ArticleSurgical neurology international2025

Cavernoma of the left ventral striatum, anatomical and microsurgical implications of the ipsilateral transcallosal transrostral pathway.

Alejandro Benjamin Romero Leguina, Luis Ángel Canache Jiménez, Mariano Teyssandier, Álvaro Rodrigo Quiñones Céspedes, Sebastian Juan Mária Giovannini, Mariela Cecilia Salerno, Erica Antunes Effgen, Érico Samuel Gomes Galvão da Trindade, José Maria de Campos Filho, Feres Chaddad-Neto

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In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Alejandro Benjamin Romero LeguinaDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Luis Ángel Canache JiménezDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Mariano TeyssandierDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Álvaro Rodrigo Quiñones CéspedesDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Sebastian Juan Mária GiovanniniDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Mariela Cecilia SalernoDepartment of Neurosurgery, Hospital de Niños Sor Maria Ludovica, La Plata, Buenos Aires, Argentina.
Erica Antunes EffgenDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Érico Samuel Gomes Galvão da TrindadeDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
José Maria de Campos FilhoDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.
Feres Chaddad-NetoDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cerebral cavernous malformations are vascular abnormalities of the central nervous system with an incidence of 0.4-0.5% and an annual hemorrhage rate ranging from 0.7% to 1%. The most important and consistent risk factor for rebleeding is a prior hemorrhage, and deep lesions (within the thalamus, basal ganglia, and brainstem) characteristically carry a worse prognosis regarding annual hemorrhage rates (10.6% per patient per year vs 0.4% per patient per year for superficial cerebral lesions) and subsequent neurologic deterioration. The ventral striatum is a difficult region to approach. The conservative treatment and also radiosurgery are not compatible with this kind of lesion, in the virtue of the eloquence and high risk of rebleeding, and the worsening of the perilesional edema, respectively, resulting in a motor deficit. Case Description: This video presents a case of a 37-year-old male patient with a 6-month history of headaches, with a magnetic resonance imaging (MRI) showing a lesion in the left ventral striatum compatible with cavernoma with signs of recent bleeding. The patient underwent an ipsilateral transcallosal transrostral approach. The procedure was uneventful, and the patient was discharged without neurological deficits. A postoperative MRI confirmed complete resection. Conclusion: The anatomical aspects to consider are analyzed as the dissection progresses toward the lesion, and the other surgical alternatives are studied in this video. The ipsilateral transcallosal transrostral pathway permits an intuitive awareness of the midline at all times, facilitating safer manipulation of the brain tissue when accessing deep-seated lesions. Consequently, the risk of intraoperative and postoperative complications decreases.

Indexed as

Anatomical aspectsCavernous malformationInterhemisphericIpsilateralVascular neurosurgeryVentral striatum

Identifiers

PMID40469318
PMCPMC12134876

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.