ReviewFrontiers in oncology2025
Preventing and managing pharyngocutaneous fistula after total laryngectomy - A narrative review.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Stapler versus manual closure for pharyngeal repair after total laryngectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Pooled it
- Impact of advanced age on quality of life and functional recovery trajectories following partial laryngectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- A clinically interpretable model for predicting pharyngocutaneous fistula after total laryngectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Pharyngeal and Cervical Reconstruction and Fistula Management Following Total Laryngectomy: Contemporary Strategies and Evidence.Life (Basel, Switzerland) · 2026Review
- Second or subsequent microvascular free flaps in head and neck reconstructive surgery: a narrative review.Annals of medicine and surgery (2012) · 2026Article
- Review
- Association of preoperative hemoglobin levels with the risk of pharyngocutaneous fistula after surgery for laryngeal and hypopharyngeal squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Safety of Primary Tracheoesophageal Puncture in Patients Submitted to Enlarged Total Laryngectomy with Pectoralis Major Reconstruction.Journal of personalized medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pharyngocutaneous fistula (PCF) remains one of the most frequent and serious complications following total laryngectomy (TL). PCF can lead to severe health issues such as infections and thromboembolic events prolonging hospitalization, as well as to life-threatening large neck vessels blowout and mediastinitis. Despite technical advancements, PCF rate after TL remains around 10%, underlining its challenges in terms of prevention and management. Numerous studies have identified risk factors contributing to PCF development: they can be distinguished into patient-, tumor-, and surgical technique related variables. Nevertheless, a wide consensus has yet to be reached for most of them. Two of the most encountered and recognized risk factors are certainly represented by salvage setting after failure of (C)RT and extension of TL to oro-, hypopharynx or cervical esophagus. In the first scenario, the use of both pedicled and free flaps either with an onlay or an inlay technique have been described, while in case of extended TL, general consensus has been reached in favor of inlay free flaps. Simultaneous use of salivary bypass tube is another commonly applied tool for PCF prevention. This review aims to describe current strategies for prevention and management of PCF after primary and salvage TL with possible extension to adjacent sites.
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