Evidence map›Paper›PMID 40469124›Full record

ArticlePakistan journal of medical sciences2025

Retrospective analysis of the efficacy of total glycosides of paeony capsules combined with hydroxychloroquine in patients with primary Sjogren's syndrome.

Tianxiao Fu, Wenwen Lu, Danbin Wu, Guolin Wu

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tianxiao FuTianxiao Fu Department of Traditional Chinese Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wenwen LuWenwen Lu Department of Traditional Chinese Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Danbin WuDanbin Wu Department of Traditional Chinese Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guolin WuGuolin Wu Department of Traditional Chinese Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In this retrospective analysis, total glucosides of paeony (TGP) were compared with hydroxychloroquine (HCQ) in the treatment of patients with primary Sjogren's syndrome (pSS). Methods: In this retrospectively analysis, 157 patients with SS treated at the First Affiliated Hospital of Zhejiang University School of Medicine hospital between January 2020 and December 2023 were included. The analysis included the flow rates of saliva and tears before and after treatment in the control group and observation group, as well as levels of white blood cells (WB), hemoglobin (Hb), platelets (PLT), and immunoinflammatory indicators including erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and serum immunoglobulin G (IgG) levels, disease evaluation scores and occurrence of adverse reactions. Results: Clinical baseline data were not statistically significant after six months of treatment between the two groups ( Conclusions: In the treatment of pSS, TGP capsules and HCQ are combined to improve salivary and lacrimal gland function, suppress the release of inflammatory factors, repair damage to the blood system, control disease activity, show significant clinical efficacy, and have few adverse reactions.

Indexed as

HCQpSSRetrospective studyTGP

Identifiers

PMID40469124
PMCPMC12130948

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.