Evidence map›Paper›PMID 40469090›Full record

Article3 Biotech2025

Response surface methodology-based approach for enhanced C-Phycocyanin production from

Santhosh Sigamani, Ragavendran Chinnasamy, Balashanmugam Pannerselvam, Hemalatha Natarajan, Dhandapani Ramamurthy

Abstract read
In one paragraph

Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Santhosh SigamaniCenter for Pharmaceutical Biotechnology, College of Medicine and Pharmacy, Duy Tan University, Da Nang, Vietnam.ORCID 0000-0002-8466-3164
Ragavendran ChinnasamyDepartment of Cariology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu India.
Balashanmugam PannerselvamAvigen Biotech Pvt Ltd, Chennai, Tamil Nadu India.
Hemalatha NatarajanDepartment of Microbiology, School of Biosciences, Periyar University, Salem, Tamil Nadu India.
Dhandapani RamamurthyDepartment of Microbiology, School of Biosciences, Periyar University, Salem, Tamil Nadu India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focuses mainly on the extraction of C-Phycocyanin (CPC) pigment from cyanobacteria, its optimization and evaluation of its radical scavenging and antiproliferative abilities. Optimization of the pigment production was conducted both experimentally and statistically by response surface methodology (RSM). Quadratic models were fitted to the responses obtained from the box-Behnken design (BBD), to examine the interactions among Carbon, Nitrogen, Phosphate, pH and Temperature, and their impact on pigment production. Analysis of variance (ANOVA) validated the model,revealing that higher levels of carbon, nitrogen and phosphate significantly influenced ( Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-025-04357-8.

Indexed as

AntioxidantApoptosisC-PhycocyaninDAPIFTIRRSMSDS-PAGE

Identifiers

PMID40469090
PMCPMC12130424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.