Evidence map›Paper›PMID 40469079›Full record

ReviewFrontiers in molecular biosciences2025

A comprehensive review of diagnostic approaches for hepatitis D.

Wen-Hui Liu, Jia-Yue Cui, Miao Yu, Xiao-Dong Shi, Yi-Lin Che, Chu-Yan Wang, Xiu-Mei Chi

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Wen-Hui Liu *Core Facility of the First Hospital of Jilin University, Changchun, China.
Jia-Yue Cui *Department of Histology and Embryology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Miao YuCore Facility of the First Hospital of Jilin University, Changchun, China.
Xiao-Dong ShiDepartment of Rheumatology and Immunology, First Hospital of Jilin University, Changchun, China.
Yi-Lin CheSchool of Public Health Jilin University, Changchun, China.
Chu-Yan WangCore Facility of the First Hospital of Jilin University, Changchun, China.
Xiu-Mei ChiCore Facility of the First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current estimates suggest 9 million to 19 million people worldwide are affected by Hepatitis D virus (HDV) infection, though significant discrepancies in diagnostic guideline implementation across regions and countries indicate these figures may not fully capture the true disease burden. HDV coinfection and superinfection with hepatitis B hasten disease progression, increasing cirrhosis and liver cancer risks, highlighting the importance of early and precise diagnosis. We present a thorough analysis of current and emerging hepatitis D diagnostic methods. Initial diagnosis involves detecting serum anti-HDV antibodies using radioisotope- or enzyme-linked immunosorbent assays. Established techniques like chemiluminescence immunoassay, quantitative microarray antibody capture, and lateral flow assays are being improved. Additional diagnostic markers include HDV antigens and RNA in the serum or liver, detectable through methods like northern and slot blots, fluorescence

Indexed as

anti-HDVdiagnosisHDAgHDVHDV RNAhepatitis Dscreening

Identifiers

PMID40469079
PMCPMC12133488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.