ArticleClinical, cosmetic and investigational dermatology2025
Rheology as a Tool to Investigate the Degradability of Hyaluronic Acid Dermal Fillers.
Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Integrative Aesthetics: Shaping the Emerging Frontier of Modern Aesthetic Medicine.Clinical, cosmetic and investigational dermatology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In the current landscape of aesthetic medicine, the use of hyaluronic acid (HA)-based dermal fillers is increasingly prevalent. Although HA is widely acknowledged for its safety and efficacy the study of its degradability represents a critical aspect in ensuring safety. Methods: Rotational rheology was chosen to study the HA-based fillers interaction with hyaluronidase enzyme; this allows to establish a correlation between the viscoelastic parameters of the sample and its degradation. Results: The obtained results indicate that the products exhibit sensitivity to the enzyme and that the rheological parameters vary depending on the contact time and dosage of administration. Conclusion: Our findings propose a standardized rheological protocol for assessing the degradability of HA-based dermal fillers, offering an alternative to existing methods.
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Registered trials
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