Evidence map›Paper›PMID 40469046›Full record

ReviewJournal of internal medicine2025

The future of healthcare-associated infection surveillance: Automated surveillance and using the potential of artificial intelligence.

Suzanne D van der Werff, Stephanie M van Rooden, Aron Henriksson, Michael Behnke, Seven J S Aghdassi, Maaike S M van Mourik, Pontus Nauclér

Abstract readReview
In one paragraph

Review in Journal of internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Beyond the Reported Numbers:Antibiotics (Basel, Switzerland) · 2026
    Article
  4. Review
  5. First results of a national deployment of a fully automated central-line-associated bloodstream infection (CLABSI) surveillance system, Switzerland, 2022 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suzanne D van der WerffDepartment of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7162-3844
Stephanie M van RoodenDepartment of Epidemiology and Surveillance, Centre for Infectious Disease Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.ORCID https://orcid.org/0000-0002-3693-3991
Aron HenrikssonDepartment of Computer and Systems Sciences, Stockholm University, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9731-1048
Michael BehnkeInstitute of Hygiene and Environmental Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-3993-9651
Seven J S AghdassiInstitute of Hygiene and Environmental Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-8263-3455
Maaike S M van MourikDepartment of Medical Microbiology and Infection Prevention, University Medical Centre Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0003-2465-4132
Pontus NauclérDepartment of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-8185-2648

Funding

Berlin Institute of HealthDFG, the Charité Universitätsmedizin - BerlinMinisterie van Volksgezondheid, Welzijn en Sport 331724Region Stockholm 2019-1054Vetenskapsrådet 2021-02271VINNOVA 2021-02699
6 · The paper itself

Abstract

Healthcare-associated infections (HAIs) are common adverse events, and surveillance is considered a core component of effective HAI reduction programmes. Recently, efforts have focused on automating the traditional manual surveillance process by utilizing data from electronic health record (EHR) systems. Using EHR data for automated surveillance, algorithms have been developed to identify patients with (ventilator-associated) pneumonia and (catheter-related) bloodstream, surgical site, (catheter-associated) urinary tract and Clostridioides difficile infections (sensitivity 54.2%-100%, specificity 63.5%-100%). Mostly methods based on natural language processing have been applied to extract information from unstructured clinical information. Further developments in artificial intelligence (AI), such as large language models, are expected to support and improve different aspects within the surveillance process; for example, more precise identification of patients with HAI. However, AI-based methods have been applied less frequently in automated surveillance and more frequently for (early) prediction, particularly for sepsis. Despite heterogeneity in settings, populations, definitions and model designs, AI-based models have shown promising results, with moderate to very good performance (accuracy 61%-99%) and predicted sepsis within 0-40 h before onset. AI-based prediction models detecting patients at risk of developing different HAIs should be explored further. The continuous evolution of AI and automation will transform HAI surveillance and prediction, offering more objective and timely infection rates and predictions. The implementation of (AI-supported) automated surveillance and prediction systems for HAI in daily practice remains scarce. Successful development and implementation of these systems demand meeting requirements related to technical capabilities, governance, practical and regulatory considerations and quality monitoring.

Indexed as

Artificial IntelligenceCross InfectionPopulation SurveillanceAlgorithmsCatheter-Related InfectionsElectronic Health RecordsHumansartificial intelligenceautomated surveillanceearly predictionhealthcare‐associated infectionssepsis

Identifiers

PMID40469046
PMCPMC12239059

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.