Evidence map›Paper›PMID 40468908›Full record

ArticleJournal of movement disorders2025

MRI-Guided Focused Ultrasound in Parkinson's Disease and Essential Tremor: Incisionless but Invasive. A Narrative Review.

Vinod Metta, Hani Taha Sherif Benamer, Georgios Kapsas, Rukmini Mridula, Rajesh Alugolu, Hasna Hussain, Afsal Nalarakettil, Sampath Kumar Natuva Sai, Mohamed Elmahdy, Rupam Borgohain and 1 more

Abstract read
In one paragraph

Article in Journal of movement disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vinod MettaKing's College London, Department of Neurosciences, Institute of Psychiatry, Psychology & Neuroscience and Parkinson's Foundation Center of Excellence, King's College Hospital, London, United Kingdom.
Hani Taha Sherif BenamerCollege of Medicine, Mohammed Bin Rashid, University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Georgios KapsasParkinson's Center of Excellence, King's College Hospital London-Dubai, United Arab Emirates.
Rukmini MridulaInstitute of Movement Disorders and Parkinson's Center, City Neuro Center, Hyderabad, India.
Rajesh AlugoluInstitute of Movement Disorders and Parkinson's Center, City Neuro Center, Hyderabad, India.
Hasna HussainParkinson's Center of Excellence, King's College Hospital London-Dubai, United Arab Emirates.
Afsal NalarakettilParkinson's Center of Excellence, King's College Hospital London-Dubai, United Arab Emirates.
Sampath Kumar Natuva SaiInstitute of Movement Disorders and Parkinson's Center, Narayana Medical College and Postgraduate Center, Andhra Pradesh, India.
Mohamed ElmahdyBahrain Specialist Hospital, Manama, Bahrain.
Rupam BorgohainInstitute of Movement Disorders and Parkinson's Center, City Neuro Center, Hyderabad, India.
Kallol Ray ChaudhuriKing's College London, Department of Neurosciences, Institute of Psychiatry, Psychology & Neuroscience and Parkinson's Foundation Center of Excellence, King's College Hospital, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance-guided focused ultrasound (MRgFUS) is an emerging and promising technology for treating movement disorders, such as essential tremors and tremor-dominant Parkinson's disease. MRgFUS utilizes advanced ultrasound transducer emitters to condense sound waves at a precisely defined point. This technology can target various brain areas, such as the pallidothalamic tract, thalamus, and pallidum, to ameliorate some of the symptoms of Parkinson's disease and other movement disorders, such as dystonic and action-induced tremors. We review the current status of preclinical and clinical trials on the clinical use, treatment outcomes, and indications of MRgFUS.

Indexed as

Blood-brain-barrierEssential tremorHigh-intensity focused ultrasound ablationMagnetic resonance-guided focused ultrasoundTremor dominant Parkinson’s disease

Identifiers

PMID40468908
PMCPMC12580729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.