Evidence map›Paper›PMID 40468714›Full record

ArticleJournal of natural products2025

Jaspamide/Jasplakinolide Is Synthesized by

Zhenjian Lin, Kyle Wolf, Vinayak Agarwal, Eric W Schmidt, Jason C Kwan

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Peptide halogenation biochemistry: interfacing pharmaceutical deliverables with chemical innovation.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenjian LinDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Kyle WolfDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin─Madison, Madison, Wisconsin 53705, United States.
Vinayak AgarwalSchool of Chemistry and Biochemistry and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0002-2517-589X
Eric W SchmidtDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-5839-694X
Jason C KwanDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin─Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0001-9933-1536

Funding

Symbiosis and Chemical Diversity GenerationR35GM148283 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Eric W Schmidt · 2023 to 2026
$2.2M
Mining the cultured and uncultured biosphere for new drugsR35GM133776 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KWAN, JASON CHRISTOPHER · 2019 to 2023
$2.1M
Halogenation Biochemistry in Human and Environmental HealthR35GM142882 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI AGARWAL, VINAYAK · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM133776NIGMS NIH HHS R35 GM142882NIGMS NIH HHS R35 GM148283
6 · The paper itself

Abstract

Symbiotic bacteria produce defensive compounds found in their eukaryotic hosts, such as marine sponges. How these symbioses are formed in each sponge, their biodiversity, and their ecological roles in nature are open challenges that remain to be addressed. Here, we describe a candidate bacterial genus,

Indexed as

DepsipeptidesMyxococcalesPoriferaAnimalsMolecular StructureMultigene FamilyPeptide SynthasesSymbiosisDepsipeptidesjasplakinolidePeptide Synthases

Identifiers

PMID40468714
PMCPMC12212067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.