ArticlePlant communications2025
A high-quality genome assembly of the tetraploid Teucrium chamaedrys unveils a recent whole-genome duplication and a large biosynthetic gene cluster for diterpenoid metabolism.
Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Teucrium chamaedrys, commonly known as wall germander, is a small woody shrub native to the Mediterranean region. Its name is derived from the Greek words meaning "ground oak," as its tiny leaves resemble those of an oak tree. Teucrium species are prolific producers of diterpenes, endowing them with valuable properties widely utilized in traditional and modern medicine. Sequencing and assembly of the 3-Gbp tetraploid T. chamaedrys genome revealed 74 diterpene synthase genes, with a substantial number of these genes clustered at four synteny genomic loci, each harboring a copy of a large diterpene biosynthetic gene cluster. Comparative genomics revealed that this cluster is conserved in the closely related species Teucrium marum. Along with the presence of several cytochrome p450 sequences, this region is among the largest biosynthetic gene clusters identified. Teucrium is well known for accumulating clerodane-type diterpenoids, which are produced from a kolavenyl diphosphate precursor. To elucidate the complex biosynthetic pathways of these medicinal compounds, we identified and functionally characterized several kolavenyl diphosphate synthases from T. chamaedrys. The remarkable chemical diversity and tetraploid nature of T. chamaedrys make it a valuable model for studying genomic evolution and adaptation in plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.