Evidence map›Paper›PMID 40468586›Full record

ArticleMagnetic resonance in medicine2025

CEST MRI data analysis using Kolmogorov-Arnold network (KAN) and Lorentzian-KAN (LKAN) models.

Jiawen Wang, Pei Cai, Ziyan Wang, Huabin Zhang, Jianpan Huang

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiawen WangLaboratory of Advanced Imaging in Medicine (AIM), Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Pei CaiLaboratory of Advanced Imaging in Medicine (AIM), Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Ziyan WangLaboratory of Advanced Imaging in Medicine (AIM), Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Huabin ZhangLaboratory of Advanced Imaging in Medicine (AIM), Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-5170-2753
Jianpan HuangLaboratory of Advanced Imaging in Medicine (AIM), Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-4453-8764

Funding

National Natural Science Foundation of China 82402225University of Hong Kong 109000487University of Hong Kong 109001694University of Hong Kong 204610401University of Hong Kong 204610519
6 · The paper itself

Abstract

purposeTo investigate the potential of using Kolmogorov-Arnold Network (KAN) and propose Lorentzian-KAN (LKAN) for CEST MRI data analysis (CEST-KAN/CEST-LKAN).

methodsCEST MRI data acquired from 27 healthy volunteers at 3 T were used in this study. Data from 25 subjects were used for training and validation (548 865 Z-spectra), whereas the remaining two were reserved for testing (51 977 Z-spectra). The performance of multi-layer perceptron (MLP), KAN, and LKAN models was evaluated and compared to conventional multi-pool Lorentzian fitting (MPLF) method in generating ΔB

resultsThe KAN and LKAN showed higher accuracy in predicting CEST parameters compared to MLP, with average reductions in test loss of 28.37% and 32.17%, respectively. Voxel-wise correlation analysis also revealed that ΔB

conclusionThis study demonstrates the feasibility of KAN and LKAN for CEST MRI data analysis, highlighting their superiority over MLP. The findings suggest that CEST-KAN and CEST-LKAN have the potential to be robust and reliable post-analysis tools for CEST MRI in clinical settings.

Indexed as

BrainImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultAlgorithmsFemaleHealthy VolunteersHumansMaleReproducibility of ResultsYoung Adultchemical exchange saturation transfer (CEST)human brainKolmogorov‐Arnold network (KAN)Lorentzian‐KAN (LKAN)multi‐pool Lorentzian fitting (MPLF)

Identifiers

PMID40468586
PMCPMC12202730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.