Evidence map›Paper›PMID 40468524›Full record

ArticleActa oncologica (Stockholm, Sweden)2025

Comparative study of lung cancer care and survival outcomes across the Nordic countries.

Ghida Khalife, Juho Waris, Uffe Bødtger, Johan Isaksson, Kirill Neumann, Hrönn Harðardóttir, Heidi Andersén, Antti Jekunen, Maria Lovén, Tuula Vasankari and 2 more

Abstract readComparative Study
In one paragraph

Article in Acta oncologica (Stockholm, Sweden), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ghida KhalifeDepartment of Public Health, University of Helsinki, Helsinki, Finland. ghida.khalife@helsinki.fi.ORCID 0009-0003-6756-8098
Juho WarisDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Uffe BødtgerRespiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University, Hospital Roskilde & Nastved, Næstved, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-1231-9209
Johan IsakssonCentre for Research and Development, Gävle County/Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5787-0072
Kirill NeumannPulmonary Department, Akershus University Hospital, Oslo, Norway.ORCID 0009-0007-2513-0871
Hrönn HarðardóttirDepartment of Respiratory Medicine, Landspitali University Hospital, Reykjavik, Iceland.ORCID 0000-0002-1421-1461
Heidi AndersénCancer Clinic, Vaasa Central Hospital, Vaasa, Finland; Finnish Lung Health Association (FILHA), Helsinki, Finland; Faculty of Medicine, Oncology Department, University of Turku, Turku, Finland.ORCID 0000-0001-5923-5865
Antti JekunenCancer Clinic, Vaasa Central Hospital, Vaasa, Finland; Finnish Lung Health Association (FILHA), Helsinki, Finland.ORCID 0000-0002-6183-0169
Maria LovénDepartment of Public Health, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-4561-3831
Tuula VasankariFinnish Lung Health Association (FILHA), Helsinki, Finland; University of Turku, Department of Pulmonary Diseases and Clinical Allergology, Turku, Finland.ORCID 0000-0002-1413-8970
Susanna Nurmi-RantalaMSD Finland, Espoo, Finland.ORCID 0009-0003-2161-903X
Paulus TorkkiDepartment of Public Health, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-1127-4205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer (LC) is the leading cause of cancer-related deaths worldwide. Despite societal, economic and genetic similarities, 5-year age-standardized relative survival rate is lower in Finland compared to the other Nordic countries. Previous studies have identified discrepancies in LC guidelines, but research on actual care practices remains limited. We aim to address this knowledge gap by conducting a comprehensive examination of the current care practices for LC patients in the Nordic countries.

methodsWe employed a non-interventional, prospective study design. We conducted an expert workshop involving LC specialists from Finland to formulate relevant questions for a structured survey. This survey was distributed to healthcare professionals (HCPs) across Nordic hospitals and primary care units. The survey results were then analyzed, and a follow-up Nordic LC expert workshop was held to identify the most relevant factors potentially influencing LC survival outcomes.

resultsFour key differences in care practices between Finland and other Nordic countries were identified: (1) resources available in primary care units, (2) waiting times in primary care, (3) availability of novel treatments and (4) tracking of LC survival and mortality outcomes by the hospital. Finland has the lowest access to computed tomography (CT) from primary care, longest waiting times in primary care, and lacks a national outcome tracking system. Some medical doctors in Finland and Iceland highlighted observed limitations in specific cases involving access to neoadjuvant immunotherapy and chemotherapy.

interpretationSeveral factors unrelated to specialized LC care are likely contributing to poorer 5-year survival rates for LC in Finland. These findings may be applicable to other healthcare systems as well.

Indexed as

Lung NeoplasmsPractice Patterns, Physicians'FinlandHumansPrimary Health CareProspective StudiesScandinavian and Nordic CountriesSurveys and QuestionnairesSurvival Rate

Identifiers

PMID40468524
PMCPMC12160590

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.