ReviewChild and adolescent psychiatry and mental health2025
Leveraging family and caregiver support in psychedelic-assisted therapy: considerations for the treatment of adolescents.
Review in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Review
- Psilocybin-Assisted Therapy for Adolescent Anorexia Nervosa: Clinical Considerations and Emerging Models of Care.Current psychiatry reports · 2026Review
- Toward a framework for psychedelic clinical trials in adolescents.Child and adolescent psychiatry and mental health · 2026Review
- Lived experience as systems-relevant evidence in psychedelic public health.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundPsychedelic-assisted therapy (PAT) is gaining recognition as a promising intervention for treatment-refractory mental health conditions in adults. While interest in its applications for adolescents is growing, critical gaps remain in understanding safe and effective delivery of PAT to this vulnerable population, including implications for caregiver/family (used interchangeably) involvement in the intervention. Caregivers play a crucial role in adolescent mental health treatment by supporting recovery and disrupting illness-maintaining patterns. They also benefit from resources to navigate the challenges of caregiving. This review synthesizes existing literature on evidence-based adolescent mental health treatments, best practices in PAT delivery, and family systems theory to propose a framework for integrating caregivers in adolescent PAT.
conclusionCurrent literature in both PAT and adolescent mental health provides a compelling case for the direct involvement of caregivers in PAT for adolescent populations. In modern PAT, therapeutic setting (i.e., "set and setting") is increasingly recognized as essential for optimizing outcomes. Similarly, the family system serves as a critical setting that may shape PAT efficacy in adolescents. This review provides recommendations and unique considerations for the incorporation of caregivers into PAT protocols for adolescents to maximize safety and efficacy of the intervention.
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Registered trials
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