ArticleCancer imaging : the official publication of the International Cancer Imaging Society2025
Prognostic value of the pre-treatment SUVmax of
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAccurate assessment and prediction of patient prognosis, early identification of high-risk patients, and improvement of clinical outcomes for individuals with extranodal natural killer/T-cell lymphoma (ENKTCL) are critical. This study evaluates the prognostic value of a novel model combining maximum standardized uptake value (SUVmax) and absolute lymphocyte count (ALC) in ENKTCL patients.
methodsWe conducted a retrospective analysis of clinical data from 57 patients diagnosed with primary ENKTCL. Optimal cut-off values for SUVmax and ALC were determined using receiver operating characteristic (ROC) curves. Clinical characteristics were analyzed by Chi-squared tests or Fisher's exact tests. Survival analysis was performed using the Kaplan-Meier method and log-rank test, while independent prognostic factors were identified through Cox regression analysis.
resultsThe optimal cut-off values for SUVmax and ALC were established at 11.8 and 0.87 × 10
conclusionPre-treatment SUVmax and ALC can serve as valuable indicators for predicting the prognosis of ENKTCL patients. Compared to IPI, NRI, and PINK scores, the SUVmax-ALC model demonstrates superior performance in risk stratification, suggesting its potential as an effective personalized prognostic tool for ENKTCL patients.
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