ArticleGenetics, selection, evolution : GSE2025
Co-occurring microbial guilds in pig fecal microbiota: key drivers and effects on host performance.
Article in Genetics, selection, evolution : GSE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Harnessing gastrointestinal microbial co-association networks to predict feed efficiency and methane emissions across beef and dairy cattle.Microbial genomics · 2026Article
- Insights into pig resilience: the Microbiome-genetic connection.Porcine health management · 2026Review
- Ruminosignatures associated with methane emissions and feed efficiency across geographies and cattle breeds.The ISME journal · 2026Article
- Data-driven enterosignatures link gut microbiome reorganization to heat stress responses in lactating sows.Frontiers in microbiology · 2026Article
- From forest to farm: the impact of a broad spectrum of lifestyles on the porcine gut microbiota.Current research in microbial sciences · 2026Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundThe pig gut microbiota is a complex ecosystem composed of microbial guilds that remain largely unexplored. Here we decomposed the pig fecal microbiota of two cohorts of 648 healthy Duroc pigs during the transition (n = 400) and growing finish (n = 248) periods in co-occurring bacterial guilds defined as pig enterosignatures (ES).
resultsOur results indicate that fecal microbial ecosystems can accurately be described by combinations of at least six ES, driven by the Prevotella (ES-Prev), Treponema (ES-Trep), Lactobacillus (ES-Lact), Clostridium (ES-Clost), Streptococcus (ES-Strep), and UBA2810 (ES-UBA2) genera. We observed a dynamic shift with age in the composition of ES, where ES-Prev, ES-Strep, and ES-Lact seem to be core components. Our results suggest partial genetic control by the host, with heritabilities of ES composition ranging from 0.24 to 0.36. Furthermore, our findings indicate that stress on the host is associated with assembly of the ES, decreasing ES-Lact abundance, and increasing prevalence of ES-Strep. We noted a positive association of ES-Prev with growth rate at 60-days, which later evolved to become negative, impacting feed efficiency during the growing period. Remarkably, a negative association of the abundance of ES-Lact with levels of hair cortisol was also found during this period.
conclusionsOur findings provide novel insights into the pig gut microbiota and reveal novels associations with relevant porcine physiological and performance traits. Moreover, while the ES concept has proven valuable in dissecting microbial communities into assemblies of underlying microbial guilds, our results emphasize the relevance of customizing microbial interventions strategies based on the nutritional and health requirements at each stage of the porcine production cycle.
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