ArticleBMC gastroenterology2025
Feasibility, effectiveness, and safety of simultaneous side-by-side deployment of uncovered self-expandable metal stents for malignant hilar biliary obstruction: a retrospective single-center study.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalignant hilar biliary obstruction is associated with a poor prognosis, making biliary drainage important for improving the quality of life. Endoscopic simultaneous side-by-side deployment of uncovered self-expandable metal stents is a novel approach. However, reliable clinical data on this method are limited. This retrospective, single-center study aimed to evaluate the feasibility, effectiveness, and safety of simultaneous side-by-side deployment of self-expandable metal stents for malignant hilar biliary obstruction.
methodsData from all patients treated for malignant hilar biliary obstruction at our institution between May 2019 and February 2023 were retrospectively analyzed. The primary endpoints were the technical and clinical success rates, while the secondary endpoints included complications, recurrent biliary obstruction, time to recurrent obstruction, reintervention rate, and mortality.
resultsFifteen patients (mean age, 63 years; 8 men) were treated with simultaneous side-by-side deployment of metal stents for malignant hilar biliary obstruction. The location of the biliary obstruction was classified as Bismuth type III (n = 1) or IV (n = 14). Technical and clinical success rates were both 100%. Three patients underwent side-by-side placement of uncovered self-expandable metal stents using the combined percutaneous endoscopic rendezvous technique. The complication rate was 13.3%, with two patients experiencing recurrent biliary obstruction and cholangitis. The median time to recurrent obstruction was 97.5 days (range: 93-102 days). Both patients required reintervention. Moreover, the 30-day mortality rate was 6.7% (n = 1).
conclusionsEndoscopic simultaneous side-by-side deployment of uncovered self-expandable metal stents for unresectable malignant hilar biliary obstruction is feasible and safe, with high success rates. This technique not only effectively controls symptoms through successful biliary drainage, but can also be a promising option for complex anatomic situations when combined with the percutaneous endoscopic rendezvous technique.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.