Evidence map›Paper›PMID 40468170›Full record

ArticleJournal of cosmetic dermatology2025

Botanical Extract-Infused Shampoo and Hair Tonic for Hair Loss in Androgenetic Alopecia: A TREND-Compliant, Prospective Single-Arm Preexperimental Study.

Dong-Gi Choi, Woo-Chul Shin

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dong-Gi ChoiCheonho Kyunghee Korean Medicine Clinic, Seoul, Republic of Korea.
Woo-Chul ShinDepartment of Korean Rehabilitation Medicine, Kyung Hee University, College of Korean Medicine, Kyung Hee University Korean Medicine Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-8082-7558

Funding

NJY biotechnology Co
6 · The paper itself

Abstract

backgroundAndrogenetic alopecia (AGA) is the most prevalent form of hair loss, often leading to treatment discontinuation due to the adverse effects and perceived ineffectiveness of conventional treatments. Botanical extracts are gaining attention for their potential benefits in managing AGA with minimal side effects.

aimsTo evaluate the efficacy and safety of a shampoo and hair tonic containing Asacurin100, a botanical extract blend, in improving hair loss conditions in patients with AGA.

methodsA prospective single-group, pretest-posttest study was conducted with 35 male participants diagnosed with AGA at a Korean medicine clinic. Participants applied the shampoo once daily and the hair tonic two to three times daily for 6 months. Data were collected via standardized global scalp photographs and a custom-designed questionnaire assessing scalp symptoms. Statistical analyses were performed to evaluate changes in hair loss area and subjective symptoms.

resultsThe study observed reductions in hair loss area, with a mean decrease of -27.35 ± 26.31 (p < 0.0001), and improvement in all scalp symptom scores. The Patient Global Impression of Change (PGIC) revealed that 80% of participants reported "much" or "very much" improvement in hair condition. No serious adverse events were reported.

conclusionsThe findings suggest that botanical extract-infused shampoo and hair tonic are effective and well-tolerated treatments for AGA, reducing hair loss and enhancing scalp health. The results warrant further investigation through larger randomized controlled trials to validate the efficacy of plant-derived compounds for AGA.

Indexed as

AlopeciaHair PreparationsPlant ExtractsAdultHumansMaleMiddle AgedPhytotherapyProspective StudiesScalpTreatment OutcomeYoung AdultHair PreparationsPlant Extractsandrogenic alopeciabotanical extractglobal photographimage analysisTREND

Identifiers

PMID40468170
PMCPMC12137762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.