Evidence map›Paper›PMID 40468146›Full record

ArticleClinical oral investigations2025

Effect of single-visit full-mouth non-surgical therapy and risk factor analysis on long-term periodontal treatment outcomes: aretrospective study.

Obada Mandil, Abdusalam Alrmali, Khushboo Kalani, Bidisha Ray, Parth Ghataliya, Shahad Alhazmi, Robert A Levine, Muhammad H A Saleh, Hom-Lay Wang

Abstract read
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Obada MandilDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Abdusalam AlrmaliDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Khushboo KalaniDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Bidisha RayDepartment of Restorative Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Parth GhataliyaDepartment of Restorative Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Shahad AlhazmiDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Robert A LevineDepartment of Periodontics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Muhammad H A SalehDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Hom-Lay WangDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA. homlay@umich.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to evaluate the long-term effectiveness of single-visit full-mouth non-surgical therapy in managing patients with progressive periodontitis during supportive periodontal therapy (SPT), with tooth loss due to periodontitis (TLP) as the primary outcome. Secondary objectives included assessing changes in probing depth (PD) and identifying risk factors associated with TLP. MATERIALS AND

methodsA retrospective analysis was conducted using patient records from the University of Michigan School of Dentistry. Included were 283 patients (mean age: 53.2 years) with periodontal breakdown during SPT (PiKS) who underwent single-visit full-mouth ultrasonic instrumentation. The primary outcome was TLP over a mean follow-up of 19.4 years. Secondary outcomes included changes in PD (≥ 5 mm and ≥ 6 mm) and identification of risk factors for tooth loss. Statistical analyses used multilevel binary logistic regression with generalized estimating equations (GEE) and linear regression models.

resultsAmong 283 patients (mean age: 53.2 years), the mean TLP was 0.9 teeth per patient over a mean follow-up of 19.4 years. Factors significantly associated with TLP included diabetes (OR = 2.41; p = 0.013), current smoking (OR = 2.13; p = 0.025), higher periodontitis Grades B and C (OR = 3.31; p = 0.001), and Stages III-IV (OR = 8.67; p = 0.001). Baseline pocket depths (PD) ≥ 5 mm (OR = 1.13; p = 0.002) and ≥ 6 mm (OR = 1.29; p = 0.001) were also associated with higher TLP. Each additional annual SPT visit reduced the TLP risk by half (OR = 0.50; p = 0.003). PD ≥ 5 mm showed minimal increase change (0.16; p = 0.02), while depths ≥ 6 mm actually decreased (-0.10; p = 0.01).

conclusionSingle-visit full-mouth non-surgical therapy is effective for long-term management of PiKS, with low tooth loss rates. Diabetes, smoking, advanced periodontitis stage/grade, and deeper baseline pockets are key predictors of TLP. Frequent SPT visits significantly mitigate tooth loss risk. CLINICAL RELEVANCE: During (SPT) appointments, prevalent practice involves the full-mouth instrumentation of persistent periodontal pockets to disrupt microbial populations and consequently reduce the inflammatory response responsible for disease progression. This study investigates the efficacy of single-visit full-mouth instrumentation as a potential alternative to standard practices in controlling periodontal disease during SPT, which have potential benefits for patients, including reduced treatment time, improved adherence to maintenance therapy, and comprehensive management of periodontal disease. By minimizing the number of visits, this approach may enhance patient compliance while reducing the risk of reinfection from untreated sites between sessions, ultimately contributing to better long-term periodontal stability. Factors such as deeper baseline probing depths and crucial risk elements for TLP-including diabetes, smoking, and advanced stages (III-IV) and grades (B and C) of periodontitis, can play a role in TLP. Additionally, this study provides valuable insights into the customization of more intensive interventions for patients at higher risk. Our findings highlight the importance of frequent SPT visits, with each additional annual visit halving the risk of TLP. The observed reduction in PD of ≥ 6 mm following treatment indicates the significant potential of comprehensive debridement for enhancing long-term periodontal stability. This evidence supports the implementation of tailored, intensive SPT schedules, particularly for patients identified as having higher risks, thereby contributing to improved clinical outcomes in periodontal disease management.

Indexed as

PeriodontitisUltrasonic TherapyAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTooth LossTreatment OutcomePeriodontitisSmokingSupportive periodontal therapyTooth loss

Identifiers

PMID40468146
PMCPMC12137392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.