ArticleNature2025
Probing condensate microenvironments with a micropeptide killswitch.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
–field-weighted citation impact
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Who cites it
23 citing papers in PubMed.
- The thermodynamic state map of biomolecular condensates.Communications biology · 2026Review
- Condensates in fusion oncoprotein-driven leukemia: new biology and therapeutic opportunities.Trends in cancer · 2026Review
- ATRX Condensates as Candidate Organizers of Enhancer-Centered Nuclear Microenvironments in Neural Progenitors: A Hypothesis for Enhancer-Associated ATRX Function in Neural Progenitors.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Directed evolution of functional intrinsically disordered proteins.Nature chemical biology · 2026Article
- TRK-T3 condensate organization drives growth signaling.Life science alliance · 2026Article
- The emerging synergy of experimental and computational approaches for therapeutic modulation of biomolecular condensates.SLAS discovery : advancing life sciences R & D · 2026Review
- Killswitch: A universal tool to link condensate microenvironments and functions.Innovation (Cambridge (Mass.)) · 2026Review
- Article
- The transcriptional repressor Ssn6 modulates phase separation to regulate fungal gene expression.mBio · 2026Article
- Small molecules modulate the biomolecular condensates and liquid‒liquid phase separation.Acta pharmaceutica Sinica. B · 2026Review
- NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From chromosomal protein disorder to chromatin phase separation.Epigenetics & chromatin · 2026Review
- Density transitions in the regulation of transcription.Molecular cell · 2026Review
- Targeting biomolecular condensates: beyond dissolution.BMC biology · 2026Review
- Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase.Nature communications · 2026Article
- PhaSepDB 3.0: a comprehensive knowledgebase of phase separation-related proteins from AI-assisted curation.Nucleic acids research · 2026Article
- Recent Advances in Reactive Microdroplets for Clean Water and Energy.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- DynAPs and cytoplasmic assembly of axonemal dyneins.Journal of cell science · 2025Article
- Proteins driving liquid-liquid phase separation and histone modifications cooperatively associate with chromatin looping and transcriptional regulation.Epigenetics & chromatin · 2025Article
Corrections and comments
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Authors and funding
23 authors.
Yaotian ZhangMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0003-3802-0843
Ida Stöppelkamp *Max Planck Institute for Molecular Genetics, Berlin, Germany.
Pablo Fernandez-Pernas *Centre of Biological Sciences, University of Veterinary Medicine, Vienna, Austria.
Melanie Allram *Centre of Biological Sciences, University of Veterinary Medicine, Vienna, Austria.
Matthew Charman *Division of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Alexandre P MagalhaesMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0002-4097-338X
Melanie Piedavent-SalomonMax Planck Institute for Molecular Genetics, Berlin, Germany.
Gregor SommerMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0009-0008-3685-010X
Yu-Chieh SungMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0009-0001-4576-152X
Katrina MeyerMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0002-8244-6887
Nicholas GramsDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Edwin HalkoDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Shivali DongreCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
David MeierhoferMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0002-0170-868X
Michal MalszyckiMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0003-1780-5596
Ibrahim A IlikMax Planck Institute for Molecular Genetics, Berlin, Germany.
Tugce AktasMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0003-1599-9454
Matthew L KrausharMax Planck Institute for Molecular Genetics, Berlin, Germany.ORCID 0000-0002-7359-0318
Nadine VastenhouwCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-8782-9775
Matthew D WeitzmanDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Florian GrebienCentre of Biological Sciences, University of Veterinary Medicine, Vienna, Austria.ORCID 0000-0003-4289-2281
Henri NiskanenMax Planck Institute for Molecular Genetics, Berlin, Germany. niskanen@molgen.mpg.de.ORCID 0000-0002-8361-5531
Denes HniszMax Planck Institute for Molecular Genetics, Berlin, Germany. hnisz@molgen.mpg.de.ORCID 0000-0002-6256-1693
Funding
Viral modulation of epitranscriptomic mechanismsR01AI118891 · NIAID · WASHINGTON UNIVERSITY · PI GARCIA, BENJAMIN A, WEITZMAN, MATTHEW D. · 2015 to 2025
$5.4MDouble-stranded RNA during DNA virus infectionR01AI145266 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI WEITZMAN, MATTHEW D. · 2019 to 2023
$3.0MAdenovirus manipulation of cellular chromatin to overcome host responsesR01AI121321 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI WEITZMAN, MATTHEW D. · 2018 to 2022
$2.7MNIAID NIH HHS R01 AI118891NIAID NIH HHS R01 AI121321NIAID NIH HHS R01 AI145266
Abstract
Biomolecular condensates are thought to create subcellular microenvironments that have different physicochemical properties compared with their surrounding nucleoplasm or cytoplasm
Indexed as
Biomolecular CondensatesCellular MicroenvironmentPeptidesCapsid ProteinsCell Line, TumorCell NucleolusCell ProliferationHumansHydrophobic and Hydrophilic InteractionsLeukemiaNuclear ProteinsNucleophosminRibosomal ProteinsSingle-Domain AntibodiesCapsid ProteinsNPM1 protein, humanNuclear ProteinsNucleophosminPeptidesRibosomal ProteinsSingle-Domain Antibodies
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.