ArticleNature2025
Increased CSF drainage by non-invasive manipulation of cervical lymphatics.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed.
- Type I IFN dynamics orchestrate protective ICAM1iScience · 2026Article
- Central nervous system lymphatic network: from the maintenance of brain homeostasis to emerging therapeutic perspectives in neurodegenerative diseases.Translational neurodegeneration · 2026Review
- Leptomeningeal fibroblasts promote glioblastoma progression by regulating cerebrospinal fluid dynamics.Nature communications · 2026Article
- A controversial Alzheimer's surgery is said to reverse symptoms - here's what scientists know.Nature · 2026Article
- Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models.Nature biotechnology · 2026Article
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- Glymphatic system impairment in neurological disorders: potential mechanisms and therapeutic targets.Molecular biomedicine · 2026Review
- Meningeal lymphatic dysfunction in Alzheimer's disease: molecular mechanisms, clinical implications, and future perspectives.Molecular neurodegeneration · 2026Review
- Disrupted drainage in the aging brain: Meningeal lymphatic decline as a convergent axis of vulnerability.Neurobiology of aging · 2026Review
- An implantable mechano-electro cascade platform synchronizes neuro-muscle repair.Nature communications · 2026Article
- Optic nerve cerebrospinal fluid drainage via lymphatic vessels in its sheath.NPJ microgravity · 2026Article
- Article
- Efficacy and Safety of Massage Therapy for Cognitive Impairment in Patients With Autism Spectrum Disorder: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2026Article
- Olfactory immunity: defending the neural-mucosal barrier.Journal of immunology (Baltimore, Md. : 1950) · 2026Review
- Temporal Dynamics of Endothelium After Radiation Injury Reveal a Transient Pro-Angiogenic Capillary Subpopulation Associated with Skin Repair.International journal of molecular sciences · 2026Article
- Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The cribriform plate: A dynamic central nervous system-immune hub.The Journal of experimental medicine · 2026Review
- Clinical Practice and Mechanism Exploration on Traditional Chinese Spinal Manipulative Therapy for Spinal Degenerative Diseases: A Review.Chinese journal of integrative medicine · 2026Review
- Discovery of Abundant Nano-scale Lymphatic-like Vessels in Brains.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Hokyung Jin *Center for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.ORCID 0000-0002-7278-0320
Jin-Hui Yoon *Center for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.ORCID 0000-0002-9389-831X
Seon Pyo Hong *Center for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Yu Seok HwangDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Myung Jin YangCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Jieun ChoiGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Hae Jin KangCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Seung Eun BaekCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Cheolhwa JinCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Junho JungCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.
Hae Jin KimDepartment of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO, USA.
Jincheol SeoNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea.ORCID 0000-0001-8040-1944
Jinyoung WonNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea.ORCID 0000-0001-5112-6736
Kyung Seob LimFuturistic Animal Resource & Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.
Chang-Yeop JeonNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea.ORCID 0000-0002-8229-7068
Youngjeon LeeNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea.ORCID 0000-0002-5387-3441
Michael J DavisDepartment of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO, USA.ORCID 0000-0002-7992-9300
Hyung-Soon ParkDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Donald M McDonaldDepartment of Anatomy, Cardiovascular Research Institute and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0002-6985-9564
Gou Young KohCenter for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea. gykoh@kaist.ac.kr.ORCID 0000-0002-1231-1485
Funding
ENDOTHELIAL PERMEABILITY IN AIRWAY ANGIOGENESISR01HL059157 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCDONALD, DONALD M · 1998 to 2015
$5.5MLymphatic pacemaking and pumping in lymphedema: function, dysfunction, and rescueR01HL122578 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DAVIS, MICHAEL JOHN · 2015 to 2023
$4.1MAngiopoietin/Tie signaling regulation of vascular leakage in lung inflammationR01HL143896 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCDONALD, DONALD M · 2018 to 2021
$2.5MMechanisms, consequences, and reversal of abnormalities in lung lymphaticsR01HL127402 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCDONALD, DONALD M · 2015 to 2018
$2.2MNHLBI NIH HHS R01 HL059157NHLBI NIH HHS R01 HL122578NHLBI NIH HHS R01 HL127402NHLBI NIH HHS R01 HL143896
Abstract
Cerebrospinal fluid (CSF) in the subarachnoid space around the brain drains to lymph nodes in the neck, but the connections and regulation have been challenging to identify
Indexed as
Cerebrospinal FluidLymphatic VesselsLymph NodesNeckAgingAnimalsEndothelial CellsFemaleGreen Fluorescent ProteinsHomeodomain ProteinsMaleMeningesMiceNitric OxideNitric Oxide Synthase Type IIIProspero-Related Homeobox 1 ProteinGreen Fluorescent ProteinsHomeodomain ProteinsNitric OxideNitric Oxide Synthase Type IIINos3 protein, mouseProspero-Related Homeobox 1 Protein
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.