Evidence map›Paper›PMID 40468067›Full record

ArticleNature2025

Subnucleosome preference of human chromatin remodeller SMARCAD1.

Pengjing Hu, Jingxi Sun, Hongyao Sun, Kangjing Chen, Youyang Sia, Xian Xia, Qiaoran Xi, Zhucheng Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome.Acta crystallographica. Section D, Structural biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pengjing Hu *MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China.
Jingxi Sun *MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China.ORCID 0009-0000-3238-9071
Hongyao Sun *MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China.ORCID 0000-0001-7256-4989
Kangjing Chen *MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China.
Youyang SiaMOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China.
Xian XiaDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0001-9833-5017
Qiaoran XiMOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China. xiqiaoran@mail.tsinghua.edu.cn.ORCID 0000-0002-7496-4131
Zhucheng ChenMOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, P.R. China. zhucheng_chen@tsinghua.edu.cn.ORCID 0000-0002-8684-0339

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromatin remodellers are pivotal in the regulation of nucleosome dynamics in cells, and they are important for chromatin packaging, transcription, replication and DNA repair

Indexed as

Chromatin Assembly and DisassemblyCryoelectron MicroscopyDNA HelicasesNucleosomesAdenosine TriphosphateDNA-Binding ProteinsHigh Mobility Group ProteinsHistone ChaperonesHistonesHumansModels, MolecularProtein BindingSubstrate SpecificityTranscriptional Elongation FactorsAdenosine TriphosphateDNA-Binding ProteinsDNA HelicasesHigh Mobility Group ProteinsHistone ChaperonesHistonesNucleosomesSMARCAD1 protein, humanTranscriptional Elongation Factors

Identifiers

PMID40468067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.