Evidence map›Paper›PMID 40467948›Full record

ArticleObesity surgery2025

Chronic Abdominal Pain and Gastrointestinal Symptoms 12 Years After Primary Roux-en-Y Gastric Bypass: A Cross-Sectional Controlled Study.

Åsne Ask Hyldmo, Dag Arne Lihaug Hoff, Arne Wibe, Kirsti Kverndokk Bjerkan, Siren Nymo, Gjermund Johnsen, Hallvard Græslie, Jorunn Sandvik

Abstract read
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Åsne Ask HyldmoDepartment of Clinical Studies, Møre and Romsdal Hospital Trust, Ålesund, Norway. asne.ask.hyldmo@stolav.no.
Dag Arne Lihaug HoffDepartment of Clinical Studies, Møre and Romsdal Hospital Trust, Ålesund, Norway.
Arne WibeDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Kirsti Kverndokk BjerkanDepartment of Surgery, Ålesund Hospital, Møre and Romsdal Hospital Trust, Ålesund, Norway.
Siren NymoClinic of Surgery, Namsos Hospital, Nord-Trøndelag Hospital Trust, Namsos, Norway.
Gjermund JohnsenDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Hallvard GræslieClinic of Surgery, Namsos Hospital, Nord-Trøndelag Hospital Trust, Namsos, Norway.
Jorunn SandvikDepartment of Surgery, Ålesund Hospital, Møre and Romsdal Hospital Trust, Ålesund, Norway.

Funding

Liaison Committee for education, research, and innovation in Central Norway 2023-34082
6 · The paper itself

Abstract

backgroundThe knowledge on chronic abdominal pain and gastrointestinal (GI) symptoms as a long-term complication to Roux-en-Y gastric bypass (RYGB) is limited. The aim of this study was to explore the frequency and characteristics of chronic abdominal pain and GI symptoms long-term after primary RYGB compared to the general population.

methodsA cross-sectional study of patients 10-15 years after RYGB compared to a control group with a similar age and sex distribution from the HUNT4 Survey. Abdominal pain and GI symptoms were assessed with a self-reported questionnaire.

resultsA total of 496 patients were included, with a mean observation time of 11.7 ± SD 1.6 years after RYGB. The controls were 3000 participants from HUNT4. Chronic abdominal pain was reported by 162 (32.7%) RYGB patients compared to 697 (23.2%) of the controls (p < 0.001). Bloating was the most common GI symptom reported by 356 (72%) RYGB patients. Eighty-two (16.5%) RYGB patients and 302 (10.1%) controls graded chronic pain as severe (p < 0.001). Severe chronic pain after RYGB was more often located in the upper part of the abdomen in 58 (71%) patients, associated with severe nausea in 27 (33%) patients, and less often relieved after defecation in 35 (42%) patients compared to the controls (p < 0.001).

conclusionsTwelve years after RYGB, a third of patients reported chronic abdominal pain compared with a quarter of controls. Half of the participants with chronic abdominal pain in both groups rated the pain as severe. The location of severe pain and associations with other gastrointestinal symptoms differed between the two groups.

Indexed as

Abdominal PainChronic PainGastric BypassGastrointestinal DiseasesObesity, MorbidAdultCase-Control StudiesCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedSurveys and QuestionnairesBariatric surgeryChronic abdominal painGastrointestinal symptomsGeneral populationRoux-en-Y gastric bypassRYGBThe HUNT4 study

Identifiers

PMID40467948
PMCPMC12271278

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.