Trial reportScientific reports2025
Effect of transcranial direct current stimulation on swallowing improvement and cortical activity in hemispheric stroke patients: a randomized, controlled trial.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuromuscular-related interventions for post-stroke dysphagia: a comprehensive narrative review.Frontiers in neuroscience · 2026Pooled it
- Intensive Rehabilitation With Adjunctive Bilateral Anodal tDCS in Post-Stroke Dysphagia: A Multicenter Randomized Controlled Trial.European journal of neurology · 2026Trial
- Feasibility study of transcranial direct current stimulation (tDCS) efficacy in patients with neurogenic dysphagia: Study Protocol.MethodsX · 2026Article
- Task-dependent cortical responses to peripheral and central neuromodulation during water and saliva swallowing after stroke: an exploratory fNIRS pilot study.Frontiers in human neuroscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Transcranial direct current stimulation (tDCS) has been extensively utilized in the treatment of post-stroke dysphagia; however, the effect of different tDCS protocols remains uncertain. This study aims to investigate the effect of tDCS on dysphagia after hemispheric stroke and compare the effect of tDCS among three protocols. A total of 90 hemispheric stroke patients were randomized into three groups: bilateral, contralesional, and ipsilesional tDCS. Each group received anodal tDCS over the orofacial sensorimotor cortex (S1M1) of the bilateral, contralesional, and ipsilesional hemispheres, respectively, administered for 20 sessions overall, combined with exercise-based swallowing therapy. After tDCS, both the dysphagia assessment scale and the swallow severity scale showed significant improvement in all three groups (all p < 0.01). In the comparisons among the three groups, the bilateral tDCS demonstrated significantly greater improvement than the contralesional and ipsilesional tDCS group in terms of the dysphagia assessment scale (all p < 0.001), and superior to contralesional tDCS group in terms of the swallow severity scale (p = 0.019). The analysis of ApEn showed increased cortical activity in both stimulated and non-stimulated areas of bilateral hemispheres after bilateral and unilateral tDCS. Moreover, larger cortical areas of bilateral hemispheres were activated after bilateral tDCS, compared to those after unilateral tDCS.Trial registration Chinese Clinical Trial Registry Identifier: ChiCTR-TRC-14004955, 16/07/2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.