Evidence map›Paper›PMID 40467866›Full record

ArticleCommunications medicine2025

Dogs fed raw meat-based diets are vectors of drug-resistant Salmonella infection in humans.

Isabelle Bernaquez, Jeannot Dumaresq, Isabelle Picard, Colette Gaulin, Réjean Dion, Kim Weaver, Matthew Walker, Ashley Kearney, Amrita Bharat, Judith Fafard and 1 more

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Hybrid genomes of three multidrug-resistantMicrobiology resource announcements · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isabelle BernaquezLaboratoire de santé publique du Québec (LSPQ), Institut national de santé publique du Québec (INSPQ), Sainte-Anne-de-Bellevue, Canada.
Jeannot DumaresqDépartement de microbiologie-infectiologie et d'immunologie, Faculté de Médecine, Université Laval, Québec, Canada.
Isabelle PicardMinistère de l'Agriculture, des Pêcheries et de l'Alimentation du Québec (MAPAQ), Québec, Canada.
Colette GaulinDirection de la protection de la santé publique, Ministère de la Santé et des Services sociaux du Québec (MSSS), Québec, Canada.
Réjean DionLaboratoire de santé publique du Québec (LSPQ), Institut national de santé publique du Québec (INSPQ), Sainte-Anne-de-Bellevue, Canada.
Kim WeaverMinistère de l'Agriculture, des Pêcheries et de l'Alimentation du Québec (MAPAQ), Québec, Canada.
Matthew WalkerNational Microbiology Laboratory, Public Health Agency of Canada (PHAC), Winnipeg, Canada.
Ashley KearneyNational Microbiology Laboratory, Public Health Agency of Canada (PHAC), Winnipeg, Canada.
Amrita BharatNational Microbiology Laboratory, Public Health Agency of Canada (PHAC), Winnipeg, Canada.
Judith FafardLaboratoire de santé publique du Québec (LSPQ), Institut national de santé publique du Québec (INSPQ), Sainte-Anne-de-Bellevue, Canada.ORCID http://orcid.org/0000-0003-4355-1294
Sadjia BekalLaboratoire de santé publique du Québec (LSPQ), Institut national de santé publique du Québec (INSPQ), Sainte-Anne-de-Bellevue, Canada. sadjia.bekal@inspq.qc.ca.ORCID http://orcid.org/0000-0001-9840-0114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSalmonella enterica serovar 4,[5],12:i:- (S. 4,[5],12:i:-), the monophasic variant of Typhimurium, is among the most prevalent surface antigen subtypes and most frequent carriers of multidrug-resistance in Salmonella worldwide, therefore becoming a prominent public health threat.

methodsGenomic surveillance data analysis, in addition to human case and animal health investigations and food inspections from Quebec, Canada were conducted to identify the source of an emerging S. 4,[5],12:i:- cluster from 2021-2023. We performed antimicrobial susceptibility testing, whole genome sequencing, phylogeny and comparative genomic analyses to characterize this local strain.

resultsWe show that a cluster of 41 S. 4,[5],12:i:- emerged in Quebec, Canada, after acquiring a self-conjugative IncHI2A plasmid encoding extensive drug-resistance (mph(A), bla

conclusionsThis study highlights the threat of S. 4,[5],12:i:- ST34 and its raw pet food-based transmission to vulnerable human populations, where impacted veal farms and asymptomatic dogs can act as disease carriers with limited treatment options and possible environmental persistence.

Identifiers

PMID40467866
PMCPMC12137576

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.