Evidence map›Paper›PMID 40467734›Full record

ArticleScientific reports2025

NECKCHECK PROJECT: enhancing diagnostic accuracy in oropharyngeal squamous cell carcinoma through computer-based radiological tools.

Sara María Ferrero-Coloma, Julián Izquierdo-Luzón, Avelino Pereira-Expósito, Jose Antonio Quesada, Carlos Ferrero-Coloma, Manuela Sancho-Mestre, Elena Garcia-Garrigós, Vicente Gil-Guillen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara María Ferrero-ColomaOtolaryngology Department, Dr Balmis General University Hospital of Alicante, Alicante, Alicante, Spain. sara.ferrero@goumh.umh.es.
Julián Izquierdo-LuzónMedical Research Department, General University Hospital of Elda, Elda, Spain.
Avelino Pereira-ExpósitoMedical Research Department, General University Hospital of Elda, Elda, Spain.
Jose Antonio QuesadaClinical Medicine Department, Miguel Hernández University, San Juan de Alicante, Alicante, Spain.
Carlos Ferrero-ColomaAnesthesiology Department, Dr. Balmis General University Hospital of Alicante, Alicante, Spain.
Manuela Sancho-MestreOtolaryngology Department, Dr Balmis General University Hospital of Alicante, Alicante, Alicante, Spain.
Elena Garcia-GarrigósRadiology Department, Dr. Balmis General University Hospital of Alicante, Alicante, Spain.
Vicente Gil-GuillenClinical Medicine Department, Miguel Hernández University, San Juan de Alicante, Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interpretation of radiological images for head and neck tumors often lacks standardized protocols, increasing the risk of diagnostic inconsistencies. This study introduces a computerized radiological checklist designed to enhance diagnostic accuracy and standardize the evaluation of oropharyngeal squamous cell carcinoma (OPSCC) imaging among otolaryngologists (ENTs). A radiological checklist was developed based on a comprehensive literature review and digitized into an intuitive interface. A concordance study involving 15 ENTs was conducted, assessing 90 OPSCC cases in two phases: before and after using the checklist. Diagnostic agreement with radiologists was measured using Cohen's kappa coefficient, and a mixed-effects linear model evaluated accuracy improvements, accounting for patient sex, age, stage, and HPV status. The checklist significantly improved diagnostic concordance, increasing Cohen's kappa from 0.28 (95% CI: 0.09-0.46) without it to 0.66 (95% CI: 0.55-0.77) with it (p < 0.01). The mixed-effects model showed a mean improvement of 2.66 correct responses in the checklist group (SE 0.31, p < 0.001). This study supports the effectiveness of this checklist in improving the diagnostic consistency and accuracy of OPSCC imaging. This method shows promise as a practical tool to reduce errors and enhance clinical practice among ENT specialists.

Indexed as

Carcinoma, Squamous CellOropharyngeal NeoplasmsSquamous Cell Carcinoma of Head and NeckAdultAgedChecklistFemaleHumansMaleMiddle AgedChecklistClinical protocolsComputer assistedHead and neck neoplasmMedical informaticsMobile appOropharynxRadiological image interpretation

Identifiers

PMID40467734
PMCPMC12137671

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.