ArticleScientific reports2025
UPLC-HRMS-MS profiling of Ludwigia adscendens subsp. diffusa aerial parts and investigation of the anti-inflammatory effect.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Profiling metabolites of Ficus natalensis hochst. fruit by UPLC-MS/MS and evaluation of anti-inflammatory activity.Scientific reports · 2026Article
- An Overview of Metabolomic Approaches to Polyphenol Profiling for Nutraceutical Development.Molecules (Basel, Switzerland) · 2026Review
- Biomarker-based assessment of tobacco smoke exposure in Saudi females via analysis of urinary cotinine level.PloS one · 2026Article
- Traditional antidiabetic medicinal plants of Himachal Pradesh: ethnomedicinal evidence and drug-discovery potential.Frontiers in nutrition · 2026Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ludwigia adscendens subsp. diffusa (Forssk.) P.H. Raven, also known as L. stolonifera, is an aquatic herb belonging to family Onagraceae and widely distributed in canals and drains in the Nile Delta, Egypt. The main goal of the current study is to investigate the metabolic profile of L. adscendens aerial parts using ultra-high performance liquid chromatography coupled with high resolution mass spectrometry (UPLC-HRMS/MS) and investigation of its anti-inflammatory activity. A total of 168 metabolites were identified by UPLC-MS/MS analysis in negative and positive modes belonging to several phytochemical classes including phenolics (57), flavonoids (26), terpenoids (25), sterols (23), fatty acids (11), coumarins (7) organic acids (5), sugar derivatives (5), lactones (4), acids (3), and glycoside (2). The UPLC-MS analysis of L. adscendens revealed identification of a diverse array of phytochemicals which contribute to its potential pharmacological properties. The identification of bioactive metabolites in L. adscendens aerial parts including gallic acid, quercetin, ellagic acid, and betulinic acid can impart biological activities including antioxidant and anti-inflammatory activities. The anti-inflammatory activity was investigated for L. adscendens methanol and ethyl acetate extract using nitric acid inhibition assay revealing IC
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